Malaria Clinical Trial
Official title:
Cluster Randomised Trial to Compare Effectiveness of the Combined Use of Indoor Residual Spraying (IRS) and Long-lasting Insecticidal Nets (LLINs) to LLINs Alone for Malaria Prevention in Muleba District, Kagera Region, Tanzania
The study is a cluster randomised trial to compare the effectiveness of indoor residual
spraying (IRS) combined with the use of long lasting insecticidal nets (LLINs) with the
effectiveness of LLINs alone for preventing malaria infection and morbidity. The primary
outcome measure is prevalence of parasitaemia and anaemia in children aged 0.5-10 years,
measured in cross sectional surveys. Secondary outcomes include relative population density
for each mosquito vector species, malaria transmission as measured by entomological
inoculation rates (EIR) by mosquito vector species, monitoring of resistance markers
including kdr, and user acceptability of LLINs compared with IRS.
Findings from this study are expected to inform decision making so that resource utilization
can be optimised.
n/a
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