Impact of IPT With Sulfadoxin Pyrimetamin on Pregnant Women and Their Babies Outcomes in Peri-urban Areas of Bobo-Dioulasso(Burkina Faso)

Malaria, Pregnancy Clinical Trial

Official title:

Impact of Intermittent Preventive Treatment (IPT) With Sulfadoxine-pyrimethamine (SP) on the Morbidities Associated With Malaria in Pregnant Women and Newborns in Peri-urban Areas of Bobo-Dioulasso, 5 Years After Its Adoption by the National Program for Fight Against Malaria in Burkina Faso.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01255605
• Other study ID #: PIC/INSSA/UPB-01
• Status: Completed
• Phase: N/A
• First received: December 6, 2010
• Last updated: June 15, 2012
• Start date: September 2010
• Est. completion date: June 2011

Study information

• Verified date: June 2012
• Source: Université Polytechnique de Bobo-Dioulasso
• Contact: n/a
• Is FDA regulated: No
• Health authority: Burkina Faso: Ministry of Health
• Study type: Observational

Clinical Trial Summary

The purpose of this is to determine the impact of intermittent preventive treatment (IPT) with sulfadoxine-pyrimethamine (SP) on the morbidities associated with malaria in pregnant women and newborns in rural peri-urban areas of Bobo-Dioulasso, 5 years after its implemented.

Description:

Malaria in pregnant women is a crucial issue in Burkina Faso. Faced with this problem, a strategy based on the use of treated nets and intermittent preventive treatment (IPT) based on sulfadoxine-pyrimethamine (SP) was adopted in 2005. Five years after its implementation, the investigators will check whether this strategy is still effective in the preventing maternal and congenital malaria on the one hand and maternal anemia, low birth weight and prematurity on the other hand.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 772
• Est. completion date: June 2011
• Accepts healthy volunteers: No
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Residing in the health area of Lafiabougou or secteur 24

• Having agreed to give free and informed consent

Exclusion Criteria:

• Bleeding from during the pregnancy

• eclampsia

Study Design

Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Malaria
• Malaria, Pregnancy

Locations

Country	Name	City	State
Burkina Faso	Institut Supérieur des Sciences de la Santé/Université Polytechnique de Bobo-Dioulasso	Bobo-Dioulasso	Houet

Sponsors (1)

Lead Sponsor	Collaborator
Université Polytechnique de Bobo-Dioulasso

Country where clinical trial is conducted

Burkina Faso, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Peripheral and placental malaria	The investigators will check if pregnant women have any malaria parasites by making a finger prick thick respectively at antenatal clinics and at delivery. A placental thin smear will be made at delivery.	Peripheral malaria : at antenatal clinics and at delivery. Placental malaria: at delivery	No
Secondary	Maternal anemia, congenital malaria,low birth weight, prematurity.	The investigators will check pregnant women haemoglobin level.A level< 11g/dl will be considered as anemia.; Congenital malaria will be assessed through cord blood smear. Birth weight <2500g will be considered as low birth weight. Prematurity designs any birth before 37 gestation weeks.	Maternal anemia: at antenatal clinics and at delivery. Congenital malaria: at delivery. Low birth weight: at delivery. Prematurity: at delivery.	No