Enteral Nutrition and Amino Acid Absorption

Malabsorption Clinical Trial

— PEPS  

Official title:

Comparaison du Profil d'Absorption Des Acides aminés Entre Une Nutrition entérale Semi-élémentaire et Une Nutrition entérale polymérique

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02590120
• Other study ID #: 12.02.FR.NHS
• Status: Completed
• Phase: N/A
• Start date: February 2015
• Est. completion date: December 2021

Study information

• Verified date: March 2022
• Source: Nestlé
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to evaluate amino acid absorption with two different type of proteins.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 6
• Est. completion date: December 2021
• Est. primary completion date: December 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patient with gastrointestinal disorder : citrulline plasma concentration < 20 µmol/L and/or xylose plasma concentration < 1,7 mmol/L

• Patient under enteral nutrition at home

• Patient already receiving 1 L by day

Exclusion Criteria:

• Obese patient BMI > 30

• Diabetes

• Renal or liver failure

• Glucocorticoids treatment

Related Conditions & MeSH terms

• Malabsorption
• Malabsorption Syndromes

Intervention

Dietary Supplement:
• Enteral nutrition

Locations

Country	Name	City	State
France	CHU de Lille	Lille

Sponsors (1)

Lead Sponsor	Collaborator
Nestlé

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Amino acid absorption profile	Area under the curve of amino acid plasma concentration	48 hours
Secondary	Tolerance	Description and occurence of adverse events	48 hours
Secondary	Nutritional status	Retinol Binding Protein and Transthyretin dosage	48 hours
Secondary	Essentials amino acid absorption	Area under the curve of plasma concentration	48 hours
Secondary	Insulinemia evolution	Insulinemia dosage	48 hours
Secondary	Link between amino acid and insuline	Correlation coefficient	48 hours