Immunomodulatory Effects of Dexmedetomidine Infusion

Status Recruiting

Clinical Trial Summary

Anesthetic management may affect both immunostimulatory and immunosuppressive mechanisms directly by modulating immune cell function or indirectly by attenuating the stress response, Thus, the choice of anesthetic technique may affect clinical outcomes by perturbing the balance between pro- and anti-inflammatory responses,anesthetics favoring this delicate balance are thus desirable as their use may reduce postoperative complications and mortality

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Major Abdominal Surgery

Clinical Trial Details

NCT number	NCT04923737
Study type	Interventional
Source	Alexandria University
Contact	rehab A. Abd Elaziz, Ass. Prof.
Phone	01001073703
Email	trcium2002@yahoo.com
Status	Recruiting
Phase	N/A
Start date	January 1, 2022
Completion date	May 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01194492` - Albumin Kinetics in Generalized Inflammation	Phase 4
Completed	`NCT00512213` - Immunonutrition Versus Standard Enteral Nutrition Before Major Surgery	N/A
Completed	`NCT04798040` - Effects of Lavender Aromatherapy and Cold Application on Pain During Drain Removal	N/A
Completed	`NCT02337010` - Continuous Central Venous Oxygen Saturation Assisted Intraoperative Hemodynamic Management	N/A
Completed	`NCT00549419` - Arterial Pressure Based Cardiac Output for Goal-Directed Therapy in Abdominal Surgery	Phase 4
Completed	`NCT04080479` - Bolus Versus Continuous Enteral Tube Feeding	N/A
Recruiting	`NCT03295851` - Preoperative Intravenous Iron Infusion to Reduce Post-surgical Complications: a Pilot Randomised Control Trial	Phase 4
Withdrawn	`NCT01403909` - Effect of Pneumatic Intermittent Venous Compression on Fluid Volumes Infused During Major Abdominal Surgery	N/A
Recruiting	`NCT02534012` - Paravertebral Block vs. General Anesthesia for Major Abdominal Surgery	N/A
Completed	`NCT05365113` - Comparison of Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers in Major Abdominal Surgery Patients	N/A
Recruiting	`NCT05276596` - Evaluation of the Early Use of Norepinephrine in Major Abdominal Surgery on Postoperative Organ Dysfunction	N/A
Completed	`NCT01075646` - Local Anesthesia Versus Saline Serum in Surgical Incision of Colorectal or Hepatic Surgery	Phase 4
Completed	`NCT04935814` - Cardiac Output Response to Vasopressin Infusion In Abdominal Surgery Patients Under Mechanical Ventilation	Phase 4
Completed	`NCT04345354` - Observational Study of the Value of Using Obstructive Sleep Apnea-hypopnea Syndrome (CPAP) Ventilation on the Occurrence of Respiratory and Cardiovascular Complications in Patients at High Risk of Obstructive Apnea Syndrome During Postoperative Sleep Surgery of a Major Abdominal Surgery.
Recruiting	`NCT06285526` - Glycocalyx Monitoring in Major Abdominal Surgery
Completed	`NCT03166644` - Individualized Goal-directed Sufentanil Administration Versus Standard Therapy in Patients Undergoing Major Abdominal Surgery	N/A
Completed	`NCT04480775` - Triamcinolone Versus Methylprednisolone in Transversus Abdominis Plane Block	Phase 2/Phase 3
Completed	`NCT05795608` - Effectivity of Incentive Spirometry on Postoperative Pulmonary Complication After Major Abdominal Surgery	N/A
Completed	`NCT02142816` - Fluid Requirement During Surgery PVI v Doppler	N/A
Completed	`NCT01217151` - Perioperative Hemodynamic Optimization Using the NICOM Device	N/A