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Major Abdominal Surgery clinical trials

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NCT ID: NCT06456918 Completed - Clinical trials for Major Abdominal Surgery

ValidationTurkishVersionQualityofRecovery-15

ValidQoR-15
Start date: September 1, 2019
Phase:
Study type: Observational

The aim of this study was to perform a cross-cultural adaptation and psychometric evaluation of the Quality of Recovery 15 questionnaire in Turkey.

NCT ID: NCT05795608 Completed - Clinical trials for Major Abdominal Surgery

Effectivity of Incentive Spirometry on Postoperative Pulmonary Complication After Major Abdominal Surgery

Start date: July 1, 2015
Phase: N/A
Study type: Interventional

This study is the first clinical trial study in Indonesia to assess the benefits of using incentive spirometry in the incidence of pulmonary complications after major abdominal surgery. This study was a randomized clinical trial in three tertiary-level referral hospitals in Indonesia (Cipto Mangunkusumo Hospital, Fatmawati Hospital, and Persahabatan Hospital). The investigators randomly assigned adult patients who underwent major abdominal elective surgery in July-August 2015 to two groups. All study subjects were simple randomly allocated to the intervention and control groups according to the randomization table. The hypothesis of the study team was that preoperative incentive spirometry can improve the incidence of postoperative pulmonary complications in major abdominal surgery

NCT ID: NCT05365113 Completed - Blood Pressure Clinical Trials

Comparison of Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers in Major Abdominal Surgery Patients

CHARM-Bloc
Start date: March 9, 2022
Phase: N/A
Study type: Interventional

The objective of this study is to investigate the hemodynamic effects of two strategies of alveolar recruitment maneuver in patients undergoing major abdominal surgery in the operating room

NCT ID: NCT04935814 Completed - Clinical trials for Mechanical Ventilation

Cardiac Output Response to Vasopressin Infusion In Abdominal Surgery Patients Under Mechanical Ventilation

CORVaso
Start date: June 9, 2021
Phase: Phase 4
Study type: Interventional

In this study, the investigators propose to explore the hemodynamic variations induced by vasopressin and its influence on cardiac output, mean systemic pressure, and venous return resistance measured through cardiopulmonary interactions, according to the approach proposed by Guyton, in patients undergoing major abdominal surgeries.

NCT ID: NCT04798040 Completed - Clinical trials for Major Abdominal Surgery

Effects of Lavender Aromatherapy and Cold Application on Pain During Drain Removal

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

This study evaluates the effect of lavender aromatherapy and cold application on pain during drain removal. The investigators hypothesize that there is no difference in pain prevention between lavender oil inhalation and local cold application.

NCT ID: NCT04480775 Completed - Clinical trials for Major Abdominal Surgery

Triamcinolone Versus Methylprednisolone in Transversus Abdominis Plane Block

triamcinolone
Start date: July 15, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

In the current Study we will compare between triamcinolone and methylprednisolone as an additive to bupivacaine drug in ultrasound guided TAP block in major open abdominal surgery .

NCT ID: NCT04345354 Completed - Clinical trials for Major Abdominal Surgery

Observational Study of the Value of Using Obstructive Sleep Apnea-hypopnea Syndrome (CPAP) Ventilation on the Occurrence of Respiratory and Cardiovascular Complications in Patients at High Risk of Obstructive Apnea Syndrome During Postoperative Sleep Surgery of a Major Abdominal Surgery.

APNOSIS-BIS
Start date: June 14, 2016
Phase:
Study type: Observational

The presence of an obstructive sleep apnea-hypopnea syndrome (OSAHS) is a perfectly identified cardiovascular and metabolic risk factor responsible for excess mortality in patients with severe OSAHS, while life expectancy, when the SAHOS is treated by continuous positive airway pressure (CPAP) is close to that of the general population. It also represents a factor of excess mortality, little known and poorly explored, in relation to morbidity and mortality occurring during the perioperative period accompanying any general anesthesia.

NCT ID: NCT04080479 Completed - Sepsis Clinical Trials

Bolus Versus Continuous Enteral Tube Feeding

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Stress metabolisms induced by severe trauma, large abdominal surgery procedures, sepsis, etc. leads to metabolic changes, which increase energy expenditure, enhanced protein catabolism, insulin resistance. Muscle proteolysis is massively stimulated. Critically ill patients pay for survival with a loss of muscles. Enteral nutrition, especially protein delivery to critically ill, is very important for optimizing their outcome. Standard enteral feeding regiments are generally based on continuous feeding, which is thought to be better tolerated by critically ill patients with easier glycaemic control by continuous infusion of insulin, translated in less glycaemic variability. But this approach is not physiological, continuous feeding does not allow protein synthesis. Optimal protein synthesis requires a pulsatile increase in branched-chain amino acids. Bolus feeding activates the entrohormonal axis (bioactive peptides, insulin), and stimulates skeletal muscle synthesis to the maximum extent. The question is, whether bolus enteral feeding in critically ill patients with limited gastrointestinal function delivers a greater amount of protein, improves nutritional parameters, with higher quadriceps muscle layer thickness (QMLT) and muscle strength.

NCT ID: NCT03702296 Completed - Sleep Clinical Trials

Can the Use of Ear Plugs and Eye Masks Help to Improve Sleep Quality After Major Abdominal Surgery?

Start date: August 29, 2018
Phase: N/A
Study type: Interventional

The importance of good sleep has been gaining interest in critically ill patients as poor sleep is associated with increased rates of delirium, non-invasive ventilation failure and stress to the patient. The use of earplugs and eye masks has been shown to result in longer sleep time and better sleep quality. The primary outcome of this randomized control trial is to evaluate if the use of eye masks and earplugs in patients undergoing major abdominal surgery will lead to improved sleep quality. Secondary outcomes include the level of noise intensity in the various monitored units, incidence of delirium, nursing demand, length of hospitalization and anaesthetic techniques. With these findings, we hope to be able to improve patients' overall satisfaction with the healthcare received.

NCT ID: NCT03166644 Completed - Clinical trials for Major Abdominal Surgery

Individualized Goal-directed Sufentanil Administration Versus Standard Therapy in Patients Undergoing Major Abdominal Surgery

PHOENIX
Start date: July 4, 2017
Phase: N/A
Study type: Interventional

To determine whether a treatment strategy targeting an individualized sufentanil administration based on the Analgesia Nociception Index (ANI) could reduce the total dose of sufentanil during major abdominal surgery, as compared with standard practice.