Brain Blood Flow Responses During Exercise: Younger Cohort

Status Recruiting

Clinical Trial Summary

Brain blood flow will be measured during exercise using magnetic resonance imaging.

Clinical Trial Description

Over 6 million Americans are living with Alzheimer's disease and related dementias and this number is expected to reach over 13 million by 2060. Thus, there is an urgent need for interventions to prevent the development and progression of Alzheimer's disease and related dementias. Regular exercise is currently the most promising strategy as it is repeatedly shown to have neuroprotective benefits. Evidence suggests that the neuroprotective effects of exercise is the result of improved health of blood vessels. Despite the vast amount of evidence on the benefit of exercise on the peripheral vasculature, there is little information regarding brain vascular responses during exercise. This study will investigate the impact of exercise at varying intensities on brain blood flow during exercise, and will also examine the influence of age and sex. This record represents a younger cohort for the study represented in NCT05864950. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06446622
Study type	Interventional
Source	University of Wisconsin, Madison
Contact	Jill N Barnes, PhD
Phone	608-262-1654
Email	jnbarnes@wisc.edu
Status	Recruiting
Phase	N/A
Start date	April 18, 2023
Completion date	June 30, 2025

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