The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery

Magnesium Disorder Clinical Trial

Official title:

The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05903677
• Other study ID #: Preoperative magnesium and AKI
• Status: Not yet recruiting
• Start date: July 2023
• Est. completion date: July 2024

Study information

• Verified date: June 2023
• Source: Assiut University
• Contact: Mostafa Ahmed
• Phone: 01113038074
• Email: mostafakaleed21[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Detection the relationship between preoperative ionized magnesium levels and the risk of acute kidney injury after cardiac surgery.

Description:

Acute kidney injury (AKI) is a major medical problem that is of particular concern after cardiac surgery. The reported prevalence of cardiac surgery-associated acute kidney injury (CSA-AKI) is up to 30% and is independently associated with an increase of morbidity and mortality .So this study is for measuring preoperative ionized magnesium levels of patients who will undergo cardiac surgeries then measuring postoperative serum creatinine, BUN and urine output to detect if they developed AKI or not and if there is a relationship between the post cardiac surgery AKI and preoperative ionized magnesium levels.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: July 2024
• Est. primary completion date: June 2024
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. patients more than or equal 18 yrs.

2. patients undergoing cardiac surgery between July 2023 and July 2024

Exclusion Criteria:

1. patients with known Kidney disease.

2. patients less than 18 yrs

Related Conditions & MeSH terms

• Acute Kidney Injury
• Magnesium Disorder

Intervention

Other:
• magnesium levels
Detection of the relationship between cardiac surgery associated AKI and preoperative magnesium levels.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (1)

Koh HB, Jung CY, Kim HW, Kwon JY, Kim NH, Kim HJ, Jhee JH, Han SH, Yoo TH, Kang SW, Park JT. Preoperative Ionized Magnesium Levels and Risk of Acute Kidney Injury After Cardiac Surgery. Am J Kidney Dis. 2022 Nov;80(5):629-637.e1. doi: 10.1053/j.ajkd.2022.03.004. Epub 2022 Apr 23. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Post cardiac surgery AKI according to KDIGO criteria with low preoperative magnesium level	Measuring preoperative magnesium level and postoperative kidney functions in form of serum creatinine in umol/L , BUN in mmol/L and urine output ml/h to detect the relationship between preoperative low magnesium level and risk of acute kidney injury after cardiac surgery.	Baseline
Primary	Post cardiac surgery AKI according to KDIGO criteria with normal or high preoperative magnesium level	Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery.	basline
Primary	Post cardiac surgery normal kidney functions with low preoperative magnesium level	Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery.	basline