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Macular Pucker clinical trials

View clinical trials related to Macular Pucker.

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NCT ID: NCT05860985 Recruiting - Retinal Detachment Clinical Trials

Zeiss RESIGHT Disposable Lenses Evaluation Study

RESIGHT
Start date: April 11, 2023
Phase: N/A
Study type: Interventional

To evaluate the intra-operative efficacy of a new intra-operative viewing device.

NCT ID: NCT05517473 Completed - Macular Holes Clinical Trials

Efficacy and Safety Evaluation of MONOBLUE DUAL View and MONOBLUE ILM View Vital Stains

NewBlueDyes
Start date: July 5, 2022
Phase:
Study type: Observational

In this study, the investigators aim to collect data regarding the efficiency and safety of two dyes used intraoperatively in vitrectomy to stain intraocular tissues. These products have the necessary approvals to use during such operation,These are NOT experimental products.

NCT ID: NCT04802915 Recruiting - Epiretinal Membrane Clinical Trials

Intraoperative Analysis of the Central Retina in ERF

Start date: January 15, 2019
Phase: N/A
Study type: Interventional

Changes in the retinal anatomy that occur in epiretinal fibrosis have not been sufficiently studied. It is possible that epiretinal fibrosis leads not only to traction dislocation of the macula, but also to ILM anatomical disorders.

NCT ID: NCT04802265 Terminated - Epiretinal Membrane Clinical Trials

EpiRetinal Membrane Peeling and Internal Limiting Membrane

ERMP&ILM
Start date: May 21, 2021
Phase:
Study type: Observational

To study and compare visual acuity in patients undergoing removal of the epiretinal membrane with and without the removal of the internal limiting membrane at baseline versus 6 month.

NCT ID: NCT04501367 Recruiting - Vitrectomy Clinical Trials

Assessing the Efficacy and Safety fo DEXTENZA, Sustained Release Dexamethasone 0.4 mg Insert(s) for the Treatment of Pain, Inflammation, and Cystoid Macular Edema Following 27 Gauge Vitrectomy With Internal Limiting Membrane Peel for the Treatment of Retinal Edema Associated With Macular Pucker.

Start date: April 27, 2021
Phase: Phase 4
Study type: Interventional

Assessing the efficacy and safety of DEXTENZA, sustained release dexamethasone 0.4 mg inserts following 27 gauge vitrectomy with internal limiting membrane peel

NCT ID: NCT04397068 Completed - Macular Pucker Clinical Trials

Compare ELP in Patients With Elective Phaco-VTX Surgery in One Eye and a Single Lens Phaco Surgery on the Other Eye

ELP
Start date: March 1, 2016
Phase: N/A
Study type: Interventional

The aim of the study is to gain more insight into the potential impact of a vitrectomy (removal of the vitreous) on postoperative effective position of the intraocular lens (IOL). Moreover, this study can provide very useful information for the optimal lens calculation in patients undergoing lens extraction with IOL implantation (whether or not combined with a vitrectomy) should undergo.

NCT ID: NCT03934190 Completed - Macular Pucker Clinical Trials

Inner Nuclear Macular Microcyst is a Risk Factor for Macular Cystoid Changes After Phacoemulsification in Eyes With Previous Vitrectomy and Macular Pucker Removal

Start date: October 1, 2014
Phase:
Study type: Observational

To evaluate the visual acuity, macular thickness, morphological changes after cataract surgery in eyes with previous vitrectomy for macular pucker. Associated risk factors were also investigated.

NCT ID: NCT02319655 Completed - Epiretinal Membrane Clinical Trials

Morphologic Changes After Membrane Peeling With Air Tamponade and Balanced Salt Solution

Start date: June 2014
Phase: N/A
Study type: Interventional

During the last decade optical coherence tomography (OCT) extended the possibilities for in vivo macula diagnostic and was increasingly used for pre- and post-operative imaging of retinal diseases. Spectral-domain optical coherence tomography (SD-OCT) with its increased scanning speed and image-resolution provides more detailed information of microstructures in the macula. Epiretinal membrane (ERM) is a disorder involving the posterior pole of the eyeball. It can be idiopathic or caused secondarily in various ocular conditions, such as uveitis, trauma, retinal detachment or retinal vascular diseases. In patients who suffer from loss of vision and metamorphopsia, vitrectomy and membrane peeling is usually performed to remove the ERM. Different study groups showed that intraoperative use of SD-OCT is possible. Two groups already achieved to work operation microscope integrated SD-OCT setup. Due to the high axial resolution of the SD-OCT some groups reported about an increased hyporeflective zone in the subfoveal region appearing directly after the membrane peeling procedure. It was hypothesized that this phenomenon could be an expression of surgical trauma, as this hyporeflective zone disappears in follow up OCT 10 days after surgery.

NCT ID: NCT01969929 Active, not recruiting - Macular Hole Clinical Trials

Comparison of Postoperative Aqueous Flare After 20G Versus 23G Pars Plana Vitrectomy

20Gvs23G
Start date: October 2013
Phase: N/A
Study type: Interventional

To compare postoperative inflammation and breakdown of blood-retinal barrier as measured by a laser flare-cell meter in 20G versus 23G vitrectomy.

NCT ID: NCT01162356 Completed - Glaucoma Clinical Trials

Prospective Retinal and Optic Nerve Vitrectomy Evaluation (PROVE) Study

PROVE
Start date: July 2010
Phase: N/A
Study type: Observational

Since the introduction of vitrectomy in 1971, this procedure has become the third most frequently performed ophthalmic surgery. Approximately 225,000 vitrectomies are performed annually in the United States and indications continue to expand. Known long-term complications of vitrectomy are relatively few and include retinal detachment and cataract formation. Although much has been written in the literature concerning acute rises in intraocular pressure (IOP) in the immediate postoperative period, there is surprisingly little information on long term IOP outcomes after vitrectomy. A recent report by Chang given at the LXII (62) Edward Jackson Memorial Lecture hypothesized a causal relationship between vitrectomy and open-angle glaucoma (OAG) via oxidative stress exacerbated by removal of the crystalline lens. A second report by Luk and colleagues reported similar conclusions in a modified cohort. Both studies, were retrospective in nature and did not perform baseline evaluations to exclude pre-existing glaucoma. Furthermore neither study accounted for natural history. Finally, our analysis has not reproduced similar results. The primary purpose of this study is to analyze the full spectrum of optic nerve and macular changes between vitrectomized study eyes and their non-vitrectomized fellow eyes to control for natural history. Baseline evaluations will include examination by fellowship trained retina and glaucoma specialists, fundus photography, autofluorescence, optical coherence tomography (macula and optic nerve) and automated visual field testing. At 3 month then annually for 5 years after vitrectomy surgery, the cohort will undergo similar evaluation.