Treatment of Challenging Macular Holes Using Plasma Rich in Growth Factors

Status Recruiting

Clinical Trial Summary

Aim of the Study:To report the structural and visual outcomes of plasma rich in growth factors in closure of challenging macular holes

Clinical Trial Description

Challenging full thickness macular holes ( FTMH) include : Recurrent FTMH Persistent (refractory) FTMH Macular holes in eyes with pathological myopia Large macular holes with an inner diameter of more than 650 µm. Plasma rich in growth factors (PRGF) is characterized by a moderate concentration of platelets, in the absence of leukocytes. This absence of leukocytes is based on the fact that they synthesize matrix metalloproteinases, free radicals, and proinflammatory cytokines, which do not contribute and even impair the altered tissue regeneration Aim of the Study:To report the structural and visual outcomes of plasma rich in growth factors in closure of challenging macular holes ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06115005
Study type	Interventional
Source	Minia University
Contact	Zeyad A Askar, Assiss. lect
Phone	01060777052
Email	zeyadaskar@gmail.com
Status	Recruiting
Phase	Phase 2
Start date	June 1, 2022
Completion date	August 1, 2024

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