Clinicopathologic Findings for Macular Disease

Status Completed

Clinical Trial Summary

this study is to analyze and compare the ultrastructure of the retinal and vitreous plane of the epiretinal membrane and internal limiting membrane removed during macular surgery and to evaluate relation between the ultrastructure of the epiretinal membrane and internal limiting membrane and surgical outcomes.

Clinical Trial Description

prospective, interventional study and includes patients who underwent vitrectomy,peeling of an epiretinal membrane and internal limiting membrane excision with or without intraoperative intraocular ICG injection.

Excised specimens were placed on a Millipore filter, fixed in a paraformaldehyde solution, and examined by light and transmission electron microscopy. Ultrathin sections were stained with uranyl acetate-lead citrate and inspected in a Zeiss EM electron microscope. The assessment was done in a blinded, masked fashion so that the clinicians who reviewed the histologic specimens ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Macular Disease

Clinical Trial Details

NCT number	NCT00994227
Study type	Interventional
Source	Hallym University Medical Center
Contact
Status	Completed
Phase	N/A
Start date	May 2009
Completion date	June 2010

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT05497128` - Standard Cut Rate 27-Gauge System Versus Ultrahigh-Speed 27-Gauge System in Macular Surgery	N/A
Completed	`NCT01468337` - Topical Interferon Gamma-1b for Central Serous Chorioretinopathy	Phase 1/Phase 2
Recruiting	`NCT03823092` - Polarization Perception in Health and Disease. Testing a New Sight Test
Recruiting	`NCT05130385` - High Resolution Optical Coherence Tomography
Recruiting	`NCT02081339` - Cohort Study of the Clinical Course of Macular Diseases in Japanese	N/A
Completed	`NCT03376776` - Epiretinal Proliferation in Eyes With Full Thickness Macular Hole	N/A
Enrolling by invitation	`NCT04607369` - Implementation of the NEDS EyeCTester App
Completed	`NCT01510392` - CEI Van Outreach Screening Study
Completed	`NCT00286637` - Novel Diagnostics for Ocular Structure
Recruiting	`NCT05588037` - Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery	N/A
Completed	`NCT01853930` - Translation of Eye Movement Reading Training to Clinical Practice	N/A
Recruiting	`NCT02321267` - Cohort Study of the Clinical Course of Macular Diseases in Kagawa	Phase 4
Terminated	`NCT01994174` - Effect of Vascular Endothelial Growth Factor Blockers on Aqueous Humor Dynamics
Completed	`NCT03244007` - Evaluation of Retinal Microstructure Detected With Intraoperative Optical Coherence Tomography During Vitrectomy