Macular Degeneration Clinical Trial
Official title:
A Phase 3 Multicenter, Randomized, Double Masked, Sham- Controlled Clinical Trial to Assess the Safety and Efficacy of Intravitreal Administration of Zimura (Complement C5 Inhibitor) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration
The objectives of this study are to evaluate the safety and efficacy of Zimura (avacincaptad pegol) intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)
Participants will be randomized in a 1:1 ratio to the following monthly treatment groups: - Avacincaptad pegol 2 mg - Sham At Month 12, the participants in the avacincaptad pegol 2mg treatment group will be re-randomized to receive the study drug either on a monthly basis or on an every other month basis The participants initially randomized to sham treatment will continue with monthly sham administration through Month 23 All participants will have a final follow up visit at Month 24 ;
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