Lymphoma Clinical Trial
Official title:
Identification of MTAP Deletion in Archival Tumor Tissue: A Pre-Screening Study in Subjects With Advanced Solid Tumors or Lymphoma
The purpose of this study is to identify subjects with advanced solid tumors or lymphoma in which the methylthioadenosine phosphorylase (MTAP) protein has been lost.
Study AG270-PS-001 is a pre-screening study to identify subjects with advanced solid tumors
or lymphoma in which the MTAP protein has been lost. Subjects whose tumor tissue has lost the
MTAP protein may be considered for future enrollment into a Phase 1 clinical study of an
experimental drug, AG-270, that is designed to inhibit the growth of tumors lacking this
protein.
Identification of the loss of MTAP will rely solely on the evaluation of archival tumor
tissue samples by IHC. This study is therefore non-interventional
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