Lymphoma Clinical Trial
Official title:
Central Lymphoma Repository Tissue Procurement Protocol for Relapse or Recurrent Disease
RATIONALE: Collecting and storing samples of tissue from patients with non-Hodgkin lymphoma
to study in the laboratory may help the study of cancer in the future.
PURPOSE: This laboratory study is collecting and storing tissue samples from patients with
relapsed or recurrent non-Hodgkin lymphoma after treatment on a Southwest Oncology Group
(SWOG) clinical trial.
OBJECTIVES:
- Acquire fresh snap-frozen lymphoma tissue from patients with relapsed or recurrent
non-Hodgkin lymphoma after treatment on a Southwest Oncology Group (SWOG) clinical
trial.
- Establish a standard set of procedures for routine acquisition, banking, and study of
lymphoma tissues within the SWOG.
- Use repository tissue to establish clinical correlations via presently activated
phenotyping studies and future projected molecular studies assessing specimen DNA and
RNA status.
- Examine the biology of therapy failure in relationship to changes in pretreatment and
post-treatment immunophenotypic data.
OUTLINE: This is a multicenter study.
Tissues collected at biopsy are snap-frozen and archived for future molecular and genetic
studies.
PROJECTED ACCRUAL: Not specified
;
Time Perspective: Retrospective
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