Lymphoma Clinical Trial
Official title:
PHASE II TRIAL OF 9-AMINOCAMPTOTHECIN IN ADVANCED CUTANEOUS T CELL LYMPHOMA
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing
so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of aminocamptothecin in treating patients
with advanced cutaneous T-cell lymphoma.
OBJECTIVES: I. Assess the antitumor activity of aminocamptothecin (9-AC) administered by
72-hour infusion in patients with advanced cutaneous T-cell lymphoma. II. Assess the toxic
effects of 9-AC administered on this schedule.
OUTLINE: Single-Agent Chemotherapy. Aminocamptothecin, 9-AC, NSC-603071.
PROJECTED ACCRUAL: A total of 30 patients will be accrued; if no more than 1 response is
seen in the first 15 patients, the study will close. Probable duration of study is 18
months.
;
Intervention Model: Single Group Assignment, Primary Purpose: Treatment
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