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Clinical Trial Summary

This is a Phase 2, open-label, multicenter study to determine the efficacy and safety of lisocabtagene maraleucel (JCAR017) in adult subjects who have relapsed from, or are refractory to, a single line of immunochemotherapy for aggressive B-cell non-Hodgkin lymphoma (NHL) and are ineligible for hematopoietic stem cell transplant (based on age, performance status, and/or comorbidities). Subjects will receive treatment with lisocabtagene maraleucel and will be followed for 2 years for safety, pharmacokinetics and biomarkers, disease status, quality of life, and survival.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03483103
Study type Interventional
Source Juno Therapeutics, a Subsidiary of Celgene
Contact
Status Completed
Phase Phase 2
Start date July 27, 2018
Completion date December 1, 2022

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