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Clinical Trial Summary

The primary objective of this study is to asess the efficacy of Relmacabtagene autoleucel as second-line therapy in adult patients with aggressive B-cell Non-Hodgkins Lymphoma who are ineligible for haematopoietic stem cell transplantation.


Clinical Trial Description

This is an open-label, multicenter, Phase 2 study to determine the antitumor activity, PK, and safety of JWCAR029(Relmacabtagene autoleucel ) in subjects who have relapsed within 12 months from, or are refractory to, a single line of immunochemotherapy for aggressive Bcell NHL and are ineligible for HSCT (as defined in the eligibility criteria). Subjects will be treated with lymphodepleting chemotherapy and JWCAR029. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06093841
Study type Interventional
Source Shanghai Ming Ju Biotechnology Co., Ltd.
Contact Medical JWCAR029, PhD
Phone +86 21 50464201
Email JWCAR029Medical@jwtherapeutics.com
Status Not yet recruiting
Phase Phase 2
Start date November 2023
Completion date February 2027

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