Lymphedema Clinical Trial
Official title:
Evaluation of Antibacterial Soap for Treatment of Lymphedema and Elephantiasis in an Area Endemic for Lymphatic Filariasis
Introduction. Lymphatic filariasis is a devastating mosquito-transmitted parasitic disease
that causes lymphedema or elephantiasis of the leg in 15 million persons, the majority of
whom are women. In these persons, frequent bacterial infections ("acute attacks") of the
legs adversely affect physical health, economic well-being, and quality of life. Prevention
of bacterial infections through hygiene and skin care can result in significant improvements
in lymphedema and patient well-being.
Methods. To determine the extent to which antibacterial soap can help reduce the incidence
of acute bacterial infections of the lower limbs in persons with filarial lymphedema, 200
patients of the Ste. Croix Hospital lymphedema treatment clinic in Leogane, Haiti randomly
assigned to receive either antibacterial (Safeguard) or placebo (Camay) soap and acute
attacks monitored monthly for 12 months. Both groups received specific instructions on
washing and skin care.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Prevention
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