High Dose SBRT for Abdominal-Pelvic Lymph Nodal Lesions in Oligometastatic Patients

Lymph Node Cancer Metastatic Clinical Trial

Official title: Feasibility Study of High Dose Stereotactic Body Radiation Therapy (SBRT) for Lymph Nodal Lesions in Oligometastatic Patients for Genito-urinary, Gastro-intestinal and Gynaecological Cancer

Status Active, not recruiting

Clinical Trial Summary

This is a prospective, multicentric, phase II and feasibility study aimed to address early and late side effects of hypofractionated ablative radiotherapy for oligometastatic patients with lymph node metastases for genito-urinary, gastro-intestinal and gynaecological cancer.

Clinical Trial Description

The purpose of this prospective, multicentric, phase II study is to determine the feasibility of Stereotactic Body Radiation Therapy in stage IV selected oligometastatic patients, by looking at acute and late toxicity. Investigators also want to verify what is the impact of local control in irradiated metastatic foci in the context of the systemic disease, how local control can affect disease free survival and overall survival, and moreover quality of life of patients treated. ;

Related Conditions & MeSH terms

• Lymph Node Cancer Metastatic

• NCT number: NCT02570399
• Study type: Interventional
• Source: Istituto Clinico Humanitas
• Status: Active, not recruiting
• Phase: N/A
• Start date: February 26, 2015
• Completion date: December 2022