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A Randomized Trial Comparing a Ventilatory Strategy To Prevent Atelectasis Versus a Lateral Decubitus Strategy During Robotic Bronchoscopy (VESPA vs. LADS Trial)

Lung Clinical Trial

Official title:
A Randomized Trial Comparing a Ventilatory Strategy To Prevent Atelectasis Versus a Lateral Decubitus Strategy During Robotic Bronchoscopy (VESPA vs. LADS Trial)

Clinical Trial Summary

To learn if LADS is better than VESPA at preventing atelectasis during a robotic bronchoscopy.

Clinical Trial Description

Primary Objective: To compare the proportion of patients developing target-obscuring atelectasis when using a lateral decubitus strategy (LADS) vs using a ventilatory strategy to prevent atelectasis (VESPA) during robotic bronchoscopy for posteriorly-located peripheral lung lesions. Secondary Objectives: - To compare the proportion of patients with atelectasis in the target lobe in VESPA vs. LADS during robotic bronchoscopy. - To compare the proportion of patients with atelectasis obscuring 100%, 50% or more, and less than 50% of the target during robotic bronchoscopy using LADS vs. VESPA. - To compare the proportion of patients in whom a biopsy sample was not taken due to atelectasis using LADS vs. VESPA. - To compare the diagnostic yield using LADS vs. VESPA. - To compare the proportion of tool in lesion (TIL) using LADS vs. VESPA. - To compare the diagnostic accuracy (sensitivity and specificity) for malignancy using LADS vs. VESPA. - To compare the proportion of LADS-induced vs. VESPA-induced complications. - To compare the proportion of bronchoscopy-induced complications in LADS vs. VESPA. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05714033
Study type Interventional
Source M.D. Anderson Cancer Center
Contact Roberto Casal, MD
Phone (832) 287-9479
Email rfcasal@mdanderson.org
Status Recruiting
Phase N/A
Start date February 10, 2023
Completion date September 14, 2032
View Details
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