Lung Transplantation Clinical Trial
Official title:
A Prospective Randomised Two Month Trial Comparing Twho Chest Physiotherapy Protocols in Lung Transplant Recipients
Verified date | September 2005 |
Source | Bayside Health |
Contact | n/a |
Is FDA regulated | No |
Health authority | Australia: National Health and Medical Research Council |
Study type | Interventional |
Chest infection is a common complication following lung transplant (LTx). Chest
physiotherapy is widely accepted as an integral part of the management of chest infections,
however there is no evidence available regarding the effectiveness of chest physiotherapy
regimes for LTx recipients.
There is no consensus regarding whether LTx recipients should be instructed to perform
regular daily chest physiotherapy routines regardless of the presence of lung secretions (ie
prophylatically) because of the changes in mucus clearance bought about by lung transplant,
or only when they have a chest infection. Some clinicians believe that a prophylactic
regimen may be beneficial.
This research will compare two chest physiotherapy treatment regimens - our current practice
of chest physiotherapy during chest infections only (Treatment A) with an independently
performed daily chest physiotherapy regimen regardless of the presence of a chest infection
(Treatment B). From this research, we aim to develop evidence-based treatment guidelines.
Status | Completed |
Enrollment | 40 |
Est. completion date | |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 16 Years to 65 Years |
Eligibility |
Inclusion Criteria: - All lung transplant recipients treated at The Alfred will be invited to participate in the study at three weeks following lung transplantation. Exclusion Criteria: - ventilator dependent - tracheostomy insitu - pneumothorax - major myopathy - oxygen requirement of greater than 4 litres per minute - or any condition that prevents them from performing PEP mask chest physiotherapy at the time of recruitment to the study. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Australia | The Alfred Hospital | Melbourne | Victoria |
Lead Sponsor | Collaborator |
---|---|
Bayside Health |
Australia,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Lung function | |||
Primary | Chest radiographic score -Brasfield Score | |||
Primary | Bronchoscopy score | |||
Primary | Days in hospital due to chest infection | |||
Primary | Antibiotic use | |||
Primary | Quality of Life – SF-36 Health Survey | |||
Primary | Functional exercise capacity - 6 minute walk test | |||
Secondary | Patient adherence to the alternative protocols | |||
Secondary | Patient satisfaction with the alternative protocols. |
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