Primary Graft Dysfunction Score in Lung Transplantation

Status Recruiting

Clinical Trial Summary

The validity of several functional parameters, which could be included in a new PGD scoring system, will be tested in a prospective pilot study of 80 consecutive bilateral lung transplant recipients in high volume lung transplant centers. Functional parameters will be collected at different time points within the first 72hrs after lung transplantation and their accuracy in predicting clinical outcome as well as their correlation with lung water content (measured by PiCCO) will be tested. Insights will serve to generate a hypothesis (a novel PGD score), which can then be tested in future prospective trials.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03276403
Study type	Observational
Source	Medical University of Vienna
Contact	Konrad Hoetzenecker, MD, PhD
Phone	0043140400
Email	konrad.hoetzenecker@meduniwien.ac.at
Status	Recruiting
Phase	N/A
Start date	November 1, 2016
Completion date	March 1, 2018

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05526950` - Cytokine Filtration in Lung Transplantation: A Swedish National Study (GLUSorb)	N/A
Recruiting	`NCT05916495` - An Evaluation of Remote Care (Questionnaire+Hybrid) in Patients Who Are Post-lung Transplant	N/A
Enrolling by invitation	`NCT05950724` - RENAL: TNF-alpha Inhibitor for Improving Renal Dysfunction and Primary Graft Dysfunction After Lung Transplant	Early Phase 1
Active, not recruiting	`NCT05505422` - Routine Versus Selective Intraoperative ECMO in Lung Transplant	N/A
Recruiting	`NCT05081141` - HHV8 and Solid Organ Transplantation
Enrolling by invitation	`NCT04522388` - Examining the Effect of Nutritional Supplementation on Skeletal Muscle Mass in Patients Awaiting Lung Transplant	N/A
Completed	`NCT04165161` - Performance Diagnosis of a Patent Foramen Ovale During Lung Transplantation Using Transesophageal Echocardiography	N/A
Recruiting	`NCT05050955` - AlloSure Lung Assessment and Metagenomics Outcomes Study
Withdrawn	`NCT03258801` - Pirfenidone as Bridging Therapy for Lung Transplant in Patients Suffering From Idiopathic Pulmonary Fibrosis
Completed	`NCT04892719` - 4DX Functional Lung Imaging in the Diagnosis of Chronic Lung Allograft Dysfunction After Lung Transplantation	N/A
Completed	`NCT03221764` - Intraoperative Amiodarone to Prevent Atrial Fibrillation in Lung Transplant Patients	Phase 2
Active, not recruiting	`NCT04975607` - Live Music Therapy to Reduce Anxiety, Pain and Improve Sleep in Post-Operative Lung Transplant Patients: A Pilot Study	N/A
Completed	`NCT05116748` - COVID19 Vaccine in SOT Adult Recipients
Recruiting	`NCT03367221` - Physiological Response in Lung Transplant Recipients Undergoing Neurally Adjusted Ventilatory Assist	N/A
Active, not recruiting	`NCT03656926` - Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-2)	Phase 3
Completed	`NCT05242289` - Cytokine Adsorption in Lung Transplantation	N/A
Recruiting	`NCT04837339` - Diagnostic and Prognostic Biomarkers of Transplant Dysfunction in the Context of Lung Transplantation	N/A
Not yet recruiting	`NCT04377139` - Management of Cytomegalovirus (CMV) Infection in Lung Transplant Recipients (LTR)
Not yet recruiting	`NCT06399302` - Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes
Terminated	`NCT03562416` - Continuation of Nintedanib After Single Lung Transplantation in IPF Subjects	Phase 2