Lung Neoplasms Clinical Trial
Official title:
Clinical Database and Biobank of Pulmonary Ground Glass Nodules Patients With Family History, a Prospective Cohort Study.
The aim of the present prospective cohort study (GGN-F) is to study the family aggregation of pulmonary ground glass nodules via the questionnaire survey and to investigate the underlying genetic mechanism via the biobank.
In recent years, with the development of low-dose chest CT screening, more and more ground
glass nodules have been found. Meanwhile, presenting as Ground-glass nodule (GGN), the
early-stage lung adenocarcinoma patients with lung cancer family history have been emerging
increasing in recent years in East Asian.
This prospective cohort study, with both a cross-sectional and a longitudinal part, will
include patients with pulmonary ground glass nodule, which were proven malignant disease.
All participants will be asked to complete questionnaire to build the clinical database of
GGN patients with detailed family history. Furthermore, blood and surgical tumor samples will
be collected as a specific biobank. And the blood samples of other family members of
participants will be collected, with their consent and knowledge.
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