Lung Neoplasms Clinical Trial
Official title:
Methods of Computed Tomography Screening and Management of Lung Cancer in Tianjin: A Population-based Cohort Study
European lung cancer screening studies using computed tomography (CT) have shown that a management protocol based on measuring lung nodule volume and volume doubling time (VDT) is more specific for early lung cancer detection than a diameter-based protocol. However, whether this also applies to a Chinese population is unclear. The aim of this study is to compare the diagnostic performance of a volume-based protocol with a diameter-based protocol for lung cancer detection and optimize the nodule management criteria for a Chinese population.
Status | Recruiting |
Enrollment | 4000 |
Est. completion date | September 2022 |
Est. primary completion date | May 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 40 Years to 74 Years |
Eligibility |
Inclusion Criteria: - Aged 40-74 years; - Resident in the Hexi district of Tianjin city for at least 3 years; - Having no self-reported history of any malignant tumor. Exclusion Criteria: - Pregnant woman will be excluded. |
Country | Name | City | State |
---|---|---|---|
China | Tianjin Medical University Cancer Institute And Hospital | Tianjin | Tianjin |
Lead Sponsor | Collaborator |
---|---|
Tianjin Medical University Cancer Institute and Hospital | Shanghai Changzheng Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, University Medical Center Groningen |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | number of clinically diagnosed lung cancer | The number of clinically diagnosed lung cancer will be collected through the hospital information system and by contacting the participants or their relatives using a questionnaire. | at the fourth year from baseline | |
Primary | number of lung cancer death | The number of lung cancer death will be collected through the hospital information system and by contacting the relatives of the participants using a questionnaire. | at the fourth year from baseline |
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