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Lung Infection clinical trials

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NCT ID: NCT02748798 Recruiting - Asthma Clinical Trials

Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders

Start date: November 10, 2020
Phase: Early Phase 1
Study type: Interventional

The goal of this research is to optimize the MRI system to obtain ideal lung images using Hyperpolarized (HP) Noble and Inert Fluorinated Gases as contrast agents. Lung coils tuned to the frequencies of these gases will be used. This study will take place at TBRHSC in the Cardiorespiratory Department and in the Research MRI facility.

NCT ID: NCT02710383 Terminated - Pancreatitis Clinical Trials

Biomarker for Cystic Fibrosis

BioCyFi
Start date: August 20, 2018
Phase:
Study type: Observational

International, multicenter, observational, longitudinal study to identify biomarker/s for Cystic fibrosis and to explore the clinical robustness, specificity, and long-term variability of these biomarker/s

NCT ID: NCT02173613 Terminated - Lung Infection Clinical Trials

Reduction the Duration of Antibiotic Therapy in the Elderly (PROPAGE)

PROPAGE
Start date: August 2012
Phase: N/A
Study type: Interventional

The main objective is to evaluate the interest of the repeated measurement of procalcitonin in patients with pulmonary infection to reduce the duration of antibiotic therapy in comparison with a conventional clinical strategy.

NCT ID: NCT02109822 Completed - Cystic Fibrosis Clinical Trials

Pilot Observational Study to Determine Feasibility of a Standardized Treatment of Pulmonary Exacerb. in Patients With CF

STOP-OB-13
Start date: January 2014
Phase: N/A
Study type: Observational

The goal of this research study is to better understand current treatment practices for pulmonary exacerbations (lung infections) and whether the Cystic Fibrosis National Patient Registry (CFFNPR)can be used for this type of study.

NCT ID: NCT02056860 Completed - Lung Infection Clinical Trials

Detecting Lung Infections Through Vibration

Start date: February 2014
Phase: N/A
Study type: Observational

The purpose of this study is to test a lung air vibrator device for vibrating air inside the lung. This exploratory diagnostic trial will test a novel and non-invasive means of detecting lower airway infections using exhaled breath sample.

NCT ID: NCT01055847 Completed - Cystic Fibrosis Clinical Trials

Aztreonam for Inhalation (AI) in Patients With Cystic Fibrosis & P. Aeruginosa Infection

Start date: June 2003
Phase: Phase 2
Study type: Interventional

This is multicenter placebo-controlled study evaluating the safety and efficacy of AI at two dosage levels compared to placebo in CF patients with P. aeruginosa lung infection.

NCT ID: NCT00815737 Active, not recruiting - Pneumonia Clinical Trials

Effectiveness and Safety of Rhubarb for the Treatment of Patients Who Have Suffered From Cerebral Hemorrhage

Start date: January 2009
Phase: Phase 2/Phase 3
Study type: Interventional

This study will determine if rhubarb will reduced the incidence of pneumonia and improved recovery from an acute cerebral hemorrhage. The study is designed to look at both infection rate and overall recovery and recovery of motor function, for example muscle strength and coordination.

NCT ID: NCT00712166 Completed - Cystic Fibrosis Clinical Trials

Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Patients With Cystic Fibrosis, Mild Lung Disease, and P. Aeruginosa

AIR-CF4
Start date: May 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety and efficacy of a 28-day course of aztreonam for inhalation solution (AZLI) in patients with cystic fibrosis (CF), mild lung disease (forced expiratory volume in 1 second [FEV1] >75% predicted, and Pseudomonas aeruginosa (PA) infection.

NCT ID: NCT00043355 Terminated - Lung Infection Clinical Trials

Safety and Efficacy of Inhaled Interferon Gamma-1b in Pulmonary MAC Infection

Start date: December 2000
Phase: Phase 2
Study type: Interventional

The purpose of this research study is to test the safety and effectiveness of inhaled Interferon gamma-1b (IFN-g 1b), when administered for 48 weeks and in combination with oral antibiotics which may be administered for up to 72 weeks for the treatment of a lung infection caused by a bacterium called Mycobacterium avium complex . FDA has not approved Interferon gamma-1b for use in patients with MAC infection of the lungs, which is the purpose of this study.Interferon gamma-1b and similar proteins play important roles in establishing and maintaining protective immune responses against a variety of microorganisms.