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Clinical Trial Summary

This project will address rare immune mediated inflammatory diseases (IMIDs) involving the lungs, i.e. interstitial pneumonitis (IP). The main objective of this study is to assess the effects of rituximab (RTX) as a rescue therapy for progressive IMID-IP patients. The primary study parameter is pulmonary function.

The secondary objectives are to explore the application of imaging with radiolabeled RTX as early predictor for efficacy of RTX, to study the effects of RTX treatment on quality of life, and to further elucidate the pathophysiology of IMID-IP by analyzing biochemical markers.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02251964
Study type Interventional
Source St. Antonius Hospital
Contact
Status Completed
Phase Phase 2/Phase 3
Start date September 2014
Completion date February 2018

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