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Lung Collapse clinical trials

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NCT ID: NCT04506203 Completed - Lung Diseases Clinical Trials

The Accuracy of Pediatric Air Test as a Non-invasive Atelectasis Diagnostic Tool

Start date: September 10, 2020
Phase: N/A
Study type: Interventional

HYPOTHESIS: During anesthetic pre-oxygenation with high FiO2, pulmonary atelectasis occur, especially in patients < 6 years old, where FRC and pulmonary closing volume may overlap. New borns and children <1 year old are especially vulnerable. OBJECTIVES: 1. Validate "air test" as a individualized and non-invasive diagnostic method of clinically significant atelectasis in pediatrics. 2. Determine what other factors contribute to atelectasis development in pediatrics METHODS: 30 pediatric patients will be studied with ages ranged between 45 postconceptional weeks and16 years old. Baseline SpO2 and lung ultrasound will be performed for each patient upon arrival at the operating theatre before preoxygenation with FiO2 of 1.0 SpO2 will be measured 15 min after intubation during a 5 min long "air test" trial (FiO2 0.25). lung collapse will be verified by lung ultrasound at the end of the 15 min trial. Lung collapse will be eventually granted upon lung US verification by a blind researcher.

NCT ID: NCT04235231 Recruiting - Lung Collapse Clinical Trials

The Effect of Lateral Tilt on Ventilation Distribution in Lungs Assessed by Electrical Impedance Tomography

N-LAT-EIT
Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Prevention of lung inhomogeneity is an essential part of preventive strategy in neurocritical care, reducing the risks of secondary brain damage from hypoxemia, hypo/hypercapnia or pneumonia.

NCT ID: NCT03369483 Recruiting - Lung Collapse Clinical Trials

Abdominal Pressure Assessment Following Open Abdominal Surgery

AbdoPress
Start date: March 13, 2018
Phase:
Study type: Observational

During abdominal surgery, the intra abdominal pressure may increase determining lung bibasal atelectasis. The investigators hypothesized that the application of Positive End Expiratory Pressure (PEEP) promptly after extubation through Continuous Positive Airway Pressure (CPAP) would improved gas exchange, especially in those patients with abdominal pressure values close to those applied by CPAP. The investigators have therefore designed this subset study enrolling patients randomized to receive CPAP in the "Prevention of Respiratory Insufficiency after Surgical Management (PRISM)" Trial in order to ascertain the abdominal pressure in post-surgical patients (abdominal open surgery procedures) enrolled in PRISM trial. In addition they would evaluate the effects of CPAP on abdominal pressure and consequently on arterial blood gas, and whether there is a correlation between PEEP values, abdominal pressure values and arterial blood gas. One hundred patients included in CPAP group of the PRISM trial will be enrolled in this subset study. The investigators will perform measurements of the abdominal pressure an urinary catheter connected with an intra-abdominal pressure device (Uno-Meter ® - Uno-medical) in all patients undergoing on open-surgical procedures after mechanical ventilation withdrawal and extubation, 30 minutes and 4 hours after the application of CPAP.

NCT ID: NCT03314519 Completed - Lung Diseases Clinical Trials

Lung Ultrasonography vs Fiberoptic Bronchoscopy for Aiding Lung Collapse in Patient Using Double Lumen Tube

Start date: October 20, 2017
Phase: N/A
Study type: Interventional

The study contains the result from a comparison of diagnostic outcomes about lung collapse by using lung ultrasonography as a new diagnostic test compares to fiberoptic bronchoscopy as the standard test.

NCT ID: NCT03155711 Completed - Lung Collapse Clinical Trials

HFNC for Induction During Bariatric Surgery Patients.

Start date: May 5, 2017
Phase: N/A
Study type: Interventional

This study aims to compared the effects of high flow nasal during the induction and during the weaning of anesthesia on intraoperative and postoperative oxygenation and postoperative atelectasis in obese patients undergoing bariatric surgery versus the standard of care, which consists in supplemental oxygen with face mask (Venturi mask).

NCT ID: NCT03142997 Completed - Lung Collapse Clinical Trials

Spontaneous Ventilation Versus Controlled Ventilation on Lung Atelectasis in Children.

Start date: April 20, 2017
Phase: N/A
Study type: Observational

This is an observational study to compare the effect of spontaneous ventilation versus controlled ventilation on lung atelectasis using lung score measured by lung ultrasound. the study will be conducted in children hospital of Cairo University Hospitals and study population will be : children aged from one to eight years of age. primary outcome will be the lung score measured by lung ultrasound.

NCT ID: NCT03133754 Recruiting - Lung Collapse Clinical Trials

OLA to Lowest DP in Cardiac Surgery

Start date: July 10, 2017
Phase: N/A
Study type: Interventional

This study aims to compared the effects in driving pressure of an open-lung strategy with a positive end-expiratory pressure (PEEP) titrated to best driving pressure (DP) after a RM versus the recommended protective PEEP of 5 cmH2O without a recruitment manuever in non-obese patients undergoing cardiac surgery.

NCT ID: NCT02919267 Completed - Thoracic Surgery Clinical Trials

Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms

PLC-OLV
Start date: September 2016
Phase: N/A
Study type: Interventional

Lung isolation technique and one-lung ventilation (OLV) are the mainstays of thoracic anesthesia. Two principal lung isolation techniques are mainly use by clinicians, the double lumen tubes (DLT) and the bronchial blockers (BB). The physiology of lung collapse during OLV is not well described in the literature. Few publications characterized scant aspects of lung collapse, only with the use of DLT and sometime in experimental animals. Two phases of lung collapse have been described. The first phase is a quick and partial secondary to the intrinsic recoil of the lung. The second phase is the reabsorption of gas contained in the alveoli by the capillary bed. The investigators plan to describe the physiology of the second phase of lung deflation using of DLT or BB, in a human clinical context.

NCT ID: NCT02798133 Completed - Lung Collapse Clinical Trials

Open Lung Approach Versus Standard Protective Strategies

Start date: July 2014
Phase: N/A
Study type: Interventional

The aim of this study was to compare the effects of adding a recruitment maneuver (RM) to low tidal volume (VT) ventilation, with or without an individualized post-RM positive end-expiratory pressure (PEEP) setting in lung-healthy patients during anesthesia.