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Local and Peripheral Immune Responsive Landscape Induced by Local Cryoablation in Patients With Lung Adenocarcinoma

Lung Adenocarcinoma Clinical Trial

Official title:
Local and Peripheral Immune Responsive Landscape Induced by Local Cryoablation in Patients With Lung Adenocarcinoma

Clinical Trial Summary

The goal of this observational study is to learn about local and peripheral immune and metabolic changes in patients with lung adenocarcinoma undergoing cryoablation. The main question it aims to answer are: - local and peripheral immune changes in patients with lung adenocarcinoma undergoing cryoablation. - local and peripheral metabolic changes in patients with lung adenocarcinoma undergoing cryoablation. Peripheral blood, biopsy tissues of patients will be collected at the baseline and after cryoablation. Single-cell sequencing, single-cell immune bank, metabolomics and spatial metabolomics will be used to explore the local and peripheral immune changes and metabolites changes in patients with lung adenocarcinoma before and after cryoablation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06104709
Study type Observational
Source China-Japan Friendship Hospital
Contact Mingming Deng, MD
Phone 86 18801336854
Email isdeng1017@163.com
Status Not yet recruiting
Phase
Start date December 1, 2023
Completion date December 31, 2024
View Details
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