Lung Adenocarcinoma Clinical Trial
Official title:
A Single-Armed Phase II Study of Radiation and Bevacizumab Maintenance Therapy for Oligometastasis of Lung Adenocarcinoma With Negative Driver Gene
This prospective phase II study is determined to explore the efficacy and safety of radiotherapy and bevacizumab maintenance therapy for oligometastatic lung adenocarcinoma with negative driver genes
This prospective phase II study is determined to explore the efficacy and safety of
radiotherapy and bevacizumab maintenance therapy for oligometastatic lung adenocarcinoma with
negative driver genes.
The patients receive SBRT radiotherapy for the primary (if any) and metastatic lesions or
divided radiotherapy with or without concurrent chemotherapy.Bevacizumab maintenance therapy
starts 1-2 months later after the chemotherapy.The recommended dose for intravenous infusion
is 15mg/kg body weight, and the drug is given every 3 weeks until disease progression or
intolerable toxicity occurs. Toxicities will be graded according to National Cancer Institute
Common Terminology Criteria for Adverse Events (CTCAE) v. 4.0.
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