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Lumbosacral Radiculopathy clinical trials

View clinical trials related to Lumbosacral Radiculopathy.

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NCT ID: NCT05614648 Terminated - Clinical trials for Lumbosacral Radiculopathy

Sciatica Epidural Radiculopathy Experimental New Interventional TherapY Clonidine Micropellet

SERENITY CM
Start date: June 19, 2023
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and effectiveness of a new pain medication in development, clonidine micropellet. Participants will receive a single injection of either clonidine micropellet or sham injection for the treatment of low back and leg pain from sciatica.

NCT ID: NCT03514277 Terminated - Low Back Pain Clinical Trials

A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief

Start date: December 1, 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to collect information about how patients feel when doctors manage their pain after lumbar spine surgery using a combination of EXPAREL® and bupivacaine injected into the lumbar spine at the end of surgery, compared to the patients that doctors use only EXPAREL® or bupivacaine to manage their pain. This information will help doctors determine which approach works best for patients who will receive surgery in their lumbar spine in the future.

NCT ID: NCT02951377 Terminated - Sciatica Clinical Trials

Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy

Start date: October 1, 2017
Phase: Phase 1
Study type: Interventional

Aim 1: The primary aim of this study is to test the feasibility of Mechanical Diagnosis and Treatment (MDT) +/- transforaminal epidural steroid injections (TESI) on pain and disability in patients awaiting physiatry consult for lumbar radiculopathy secondary to lumbar disc herniation, compared to usual care within the current healthcare system in Calgary, Alberta, Canada. Hypothesis: the investigators hypothesise that centralisers treated with MDT and non-centralisers receiving TESIs + MDT will have demonstrate reductions in self-reported pain and disability, compared to usual care controls. Aim 2: the investigators will also describe the potential impact on healthcare resources by tracking surgical rates and self-reported healthcare utilisation during the study period. Hypothesis: based on predicted reductions in pain and disability, the investigators hypothesise that there will be a trend toward overall less healthcare utilisation (including surgery) in the MDT guided group compared to the surgical wait list group.

NCT ID: NCT01836770 Terminated - Clinical trials for Lumbosacral Radiculopathy

Epidural Contrast Flow Patterns of TESI Using the Inferior-Anterior Position as the Final Needle Tip Position.

Start date: August 2010
Phase: N/A
Study type: Observational

The purpose of this study is to describe the contrast flow patterns in the epidural space using the inferior-anterior approach with continuous fluoroscopic guidance, and determine how well this approach correlates with appropriate contrast flow patterns and with analgesia at follow up. This knowledge may prove useful in guiding physician practice patterns in the non-surgical management of low back pain. Hypothesis: The investigators hypothesize that there will be suitable (ventral/anterior) epidural contrast spread based on inferior-anterior needle-tip position, particularly with appropriate needle tip position.

NCT ID: NCT01267825 Terminated - Clinical trials for Lumbosacral Radiculopathy

CT Guided Injection for Low Back Radiculopathy: A Randomized Clinical Trial

Start date: September 1, 2010
Phase: Phase 4
Study type: Interventional

Herniated disc sometimes cause back pain radiating down to a leg. This pain can be so severe that it is functionally disabling. The purpose of this randomized clinical trial is to determine if corticosteroid medication, delivered directly to the area near the herniated disc, can improve the pain and functional disability associated with a herniated disc.