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Shaping Anesthetic Techniques to Reduce Post-operative Delirium — SHARP  

Delirium Clinical Trial

Official title:
Shaping Anesthetic Techniques to Reduce Post-Operative Delirium

Clinical Trial Summary

The purpose of this study is to determine if light sedation with spinal anesthesia reduces the incidence of delirium compared to receiving general anesthesia during spinal surgery in older adults.

Clinical Trial Description

Post-operative delirium is a common occurrence in older adults. Post -operative delirium has been associated with cognitive decline after hospitalization. Developing perioperative management strategies to prevent delirium may also reduce potential cognitive decline in older adults after surgery. The choice and dose of anesthetic and sedative drugs are known risk factors in the development of delirium. Excessive doses of anesthetic and sedation drugs during surgery have been associated with poor outcomes that occur after surgery. Currently depth of anesthesia can be measured by an additional monitoring technique called Bispectral Index (BIS).

The purpose of this study is to determine if light sedation with spinal anesthesia reduces the incidence of delirium compared to receiving general anesthesia during spinal surgery in older adults. Previous studies have shown that using light sedation and spinal anesthesia during surgery may reduce the incidence of delirium up to 50%. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03133845
Study type Interventional
Source Johns Hopkins University
Contact
Status Completed
Phase N/A
Start date October 2015
Completion date May 25, 2020
View Details
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