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Lumbar Spinal Stenosis clinical trials

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NCT ID: NCT06381167 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Endoscopic Decompression Versus Microscopic Decompression in Lumbar Canal Stenosis

Start date: May 2024
Phase: N/A
Study type: Interventional

To compare between the clinical and surgical efficacies of bi-portal endoscopic and microscopic decompressive laminectomy in patients with degenerative lumbar spinal stenosis.

NCT ID: NCT06089746 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Lumbosacral Spinal Stenosis - Non-Invasive Postural Therapy for Older Adult Veterans

LSS-NIPT
Start date: February 15, 2024
Phase: N/A
Study type: Interventional

Lumbosacral spinal stenosis (LSS) is a leading cause of limited mobility, reduced independence, and poor health outcomes in older adults, and is very common in older adult Veterans. Several years ago, major research studies indicated that surgery for LSS was more effective than usual (medical) management. Nonetheless, there are many patients for whom surgery is not the ideal therapy. There have been reports that modifications in daily activities including temporary use of a modified rolling walker and changes in sleep positioning may help relieve LSS. The investigators have assembled a VA team to study this carefully. The investigators will recruit a small group of older adult Veterans with LSS to try out this program; the investigators will monitor them closely for relief of their symptoms and improvements in walking. The investigators will, as part of this small study, try to understand potential barriers to use of this therapy. The investigators will interview the Veterans and healthcare providers to identify problems that may arise in trying this therapy. If this small study works, the investigators plan to expand the effort.

NCT ID: NCT06075355 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Can Minimally Invasive Decompression Surgery Restore Sagittal Balance in a Patient Population With Sagittal Imbalance and Lumbar Spinal Stenosis

Start date: June 30, 2024
Phase:
Study type: Observational

From adulthood onwards, the aging process manifests itself in the spine through loss of disc height and kyphotic deformity. As the general population ages, the prevalence of lumbar degenerative diseases and sagittal imbalance increases. Sagittal balance is a physiological alignment resulting from the effective muscular and ligamentary forces that place patients' heads harmoniously in line with their pelvis. Roussouly first classified this alignment by differentiating four types of balance in an asymptomatic population. He established a link between the varieties of sagittal balance of the spine, the sacral slope and the position of the pelvis in space. He went on to explain sagittal imbalance in the aging population suffering from degenerative diseases. One of the most common lumbar degenerative diseases is lumbar spinal canal stenosis. Stenosis of the lumbar spinal canal is frequently associated with sagittal imbalance of the spine. Lumbar canal stenosis causes lumbar pain, leg pain, neurogenic intermittent claudication and bladder and rectal disorders. The severity of clinical symptoms increases linearly with progressive sagittal imbalance [8]. We represent the sagittal imbalance of the spine by a positive sagittal vertical axis (SVA) presented by patients to reduce the pressure exerted by the yellow ligament, which is hypertrophied in degenerative disease . Many have shown that this forward-flexing posture can be improved by simple decompression, and that this deformity corresponds to an analgesic position and not to a structural deformity. Little is known about the factors that influence alignment after lumbar canal decompression and short segment fusion. This study therefore aims to elucidate some of the clinical and radiological factors likely to affect postoperative sagittal balance in patients undergoing simple minimally invasive decompression surgery and short segment fusion (1 or 2 levels).

NCT ID: NCT06058143 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Crenel Lateral Interbody Fusion Combined With Lateral Plate Fixation for LSS Combined With Lumbar Instability

Start date: November 2023
Phase: N/A
Study type: Interventional

At present, interbody fusion is the mainstream treatment for patients with lumbar spinal stenosis (LSS) and lumbar instability. However, the choice of interbody fusion for LSS patients with lumbar instability remains controversial. Recently, we developed crenel lateral interbody fusion combined with lateral plate fixation(CLIF - LP) for patients with LSS and lumbar instability. This surgical method has many advantages and showed good results for patients with LSS and lumbar instability. Therefore, we propose the following hypothesis: The clinical and imaging efficacy of CLIF-LP in the treatment of LSS patients with lumbar instability is not inferior to that of traditional transforaminal lumber interbody fusion (TLIF).

NCT ID: NCT06023498 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Optimizing Impact of Manual Therapy on Lumbar Spinal Stenosis

Start date: July 2024
Phase: N/A
Study type: Interventional

Lumbar spinal stenosis, a common condition in older adults, can cause pain and difficulty walking (i.e., intermittent neurogenic claudication - INC). Patients with INC not infrequently undergo spinal surgery that fails to help them 1/3-1/2 the time. The purpose of this multi-site feasibility study is to prepare for the conduct of a randomized controlled trial to test the efficacy of manual therapy, exercise, and intramuscular electroacupuncture in reducing pain and improving walking ability for those with INC, and ultimately limiting the need for surgical referrals.

NCT ID: NCT05791422 Not yet recruiting - Low Back Pain Clinical Trials

Improvement of Low Back Pain After Decompression in Patients With Degenerative Spinal Canal Stenosis

Start date: March 20, 2023
Phase:
Study type: Observational

Degenerative lumbar spine disease is a leading cause of disability in the world; it encompasses conditions such as spondylolisthesis, disc degeneration, and lumbar spinal stenosis. Those conditions present with a variety of clinical symptoms, including lower extremity pain, weakness, and low back pain (LBP) of varying levels of severity and in severe cases urine and stool incontinence may result.

NCT ID: NCT05633550 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

SPSI Validity and Test-Retest Reliability Study

Start date: August 1, 2024
Phase:
Study type: Observational

Orthopaedic surgeons are often faced with the clinical dilemma of whether or not to add fusion to a decompression procedure. To decide between these two surgical options, surgeons rely mostly on their experience to conclude if a level is unstable preoperatively or if a specific decompression procedure is likely to destabilize the spine. Recently, the Sagittal Plain Shear Index (SPSI) has been developed as a valid test for determining the degree of spinal (in)stability. The SPSI metric, which can be calculated using flexion-extension radiographs of the lumbar spine, informs the orthopaedic surgeon about whether the spine is stable in and of itself (necessitating decompression surgery only) or whether there is spinal instability (necessitating decompression and additional fusion surgery). The SPSI metric can be calculated using both the validated semi-automated QMA® and more recently developed fully automated Spine CAMP software platforms. The concurrent validity between these two software platforms, as well as the reliability of both of these objective diagnostic indicator for spinal instability have not yet been evaluated. This study will investigate if SPSI-metrics/values obtained with Spine CAMP are equivalent to measurements from QMA®, and will also investigate the repeatability of two measurements of the SPSI taken one hour apart ('test-retest reliability').

NCT ID: NCT05632835 Not yet recruiting - Low Back Pain Clinical Trials

Application of 3D Printing Guide Plate in Endoscopic Spinal Surgery

Start date: November 25, 2022
Phase: N/A
Study type: Interventional

Application of 3D printing guide plate in endoscopic spinal surgery

NCT ID: NCT05487690 Not yet recruiting - Low Back Pain Clinical Trials

Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries

Start date: October 20, 2022
Phase: N/A
Study type: Interventional

Application of 3D printing guide plate in spinal minimally invasive and interventional surgeries

NCT ID: NCT05147064 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Minimal Invasive Surgery Versus Interlaminar Decompression in Lumbar Canal Stenosis

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Conventional open surgery has been shown to be an effective procedure for LCS decompression. Minimally invasive surgery (MIS) through tubular retractors is a recently introduced alternative procedure for decompression of LCS. The current study aims at evaluating the efficacy of minimally invasive surgery as a decompressive procedure in comparison to conventional open surgery for the treatment of patients with LCS.