Comparison of Unilateral or Bilateral Fixation in the Treatment of LFS

Lumbar Foraminal Stenosis Clinical Trial

Official title: Comparison of Unilateral or Bilateral Fixation Using Pedicle Screws and TLIF in the Treatment of Lumbar Foraminal Stenosis

Status Completed

Clinical Trial Summary

TLIF is a popular lumbar fusion technique to perform interbody fusion. Pedicle screws providing initial stability have been developed to correct deformity, improve the rate of fusion and speed patient's postoperative recovery. Conventionally, bilateral pedicle screw fixation is a standard approach. Recently, studies have revealed that unilateral pedicle screw fixation provides equivalent clinical outcomes and fusion rates as compared with bilateral pedicle screw fixation in lumbar fusion. Meanwhile, the unilateral approach can reduce intraoperative blood loss and operating time. To our knowledge, few randomized controlled studies comparing unilateral versus bilateral instrumented TLIF in lumbar degenerative diseases have been reported. The purpose of this study is to compare clinical and radiographic outcomes in a series of patients with lumbar foraminal stenosis using instrumented TLIF with unilateral or bilateral pedicle screw fixation.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Constriction, Pathologic
• Lumbar Foraminal Stenosis

• NCT number: NCT02985138
• Study type: Interventional
• Source: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
• Status: Completed
• Phase: N/A
• Start date: December 2016
• Completion date: September 2021