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Lumbar Disc Herniation clinical trials

View clinical trials related to Lumbar Disc Herniation.

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NCT ID: NCT04209322 Completed - Clinical trials for Lumbar Disc Herniation

Trial of Pulsed Radiofrequency for Sciatica and Disc Herniation

PRATS
Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Transforaminal epidural injection of treatments, commonly steroids (TFESI), is offered to people with sciatica and might improve symptoms, reduce disability and speed up return to normal activities (NICE guidelines) Imaging-guided TFESI has traditionally been performed in the sciatica context because injection is administered directly to the nerve root, which relieves the pain markedly; however, the maintenance time is usually short. Treatment with radiofrequency for pain management is in clinical use since decades primarily with nerve lesioning (thermoablation) once the specific pain tributary nerve is identified. Pulsed radiofrequency (PRF) with neuromodulation intention (not lesioning) has been shown to be effective in reducing some types of chronic pain, both degenerative and neuropathic. Pulsed radiofrequency has been also extensively used in the context of acute and subacute sciatica due to disc herniation without sufficient level of evidence. In a prospective RCT, comparing prf directed to dorsal root ganglia and Tfesi in patients with sciatica did not allow conclusions on efficacy because of limitations of the trial. In that trial, only few participants completed the study due to violation of trial protocol translating the results as not consistent. One retrospective trial, in which the use of Prf in addition to tfesi was evaluated in patients with acute and subacute sciatica, demonstrated rapid pain relief onset and prolonged maintenance; the overall efficacy was superior to that of the single method treatment (either tfsei or prf). The investigators conducted a randomized, double-blind, controlled trial (Pulsed Radiofrequency in Addition to Tfesi for Sciatica [PRATS]) to determine if PRF in addition to TFESI leads to better outcomes in the management of patients with acute and subacute sciatica due to disc herniation, compared to TFESI alone.

NCT ID: NCT04207606 Completed - Clinical trials for Lumbar Spinal Stenosis

Post Epidural Steroid Injection Follow-up

Start date: January 3, 2020
Phase:
Study type: Observational

To determine the expected pain response timeline for patients receiving epidural steroid injections, our team plans to assess patient pain severity and degree of pain relief every 3 days for 23 days.

NCT ID: NCT04182997 Recruiting - Clinical trials for Lumbar Disc Herniation

Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy

Intra-Op
Start date: November 21, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine a grading system for inflammation in lumbar disc herniation and which groups, if any, benefit most from the administration of an intra-operative epidural steroid.

NCT ID: NCT04112485 Completed - Clinical trials for Lumbar Disc Herniation

Open Discectomy Versus Microscopic Discectomy for Lumbar Disc Herniation

Start date: March 4, 2015
Phase: N/A
Study type: Interventional

60 patients involved were divided into two matched groups; Group A: 30 patients were treated with conventional fenestration laminectomy and discectomy and Group B: 30 patients were treated with microdiscectomy. The age of the patients involved in this study ranged from 19 years old to 46 years old

NCT ID: NCT04083703 Not yet recruiting - Clinical trials for Lumbar Disc Herniation

Evaluation of Interbody Cage Insertion in Treatment of Lumbar Disc Prolapse

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Comparison between discectomy alone and interbody cage insertion in treatment of lumbar disc prolapse

NCT ID: NCT04073095 Completed - Clinical trials for Lumbar Disc Herniation

Erector Spinae Plane Block and Modified-Thoracolumbar Interfascial Plane Block Following Lumbar Spinal Surgery

Start date: September 13, 2019
Phase: N/A
Study type: Interventional

Ultrasound (US)-guided peripheral nerve blocks have been used increasily due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance. In this technique, local anesthetic solution is injected between the multifidus and logissimus muscles nearly at the level of the 3rd lumbar vertebra and targets the dorsal rami of the thoracolumbar nerves. However, the visualisation of this technique may be difficult under US guidance. Therefore, modified-TLIP (mTLIP) block was defined as a new approach. It has been reported that mTLIP block may provide effective analgesia management after lumbar spine surgery. The ultrasound (US) guided erector spina plane block (ESPB) is a novel interfacial plan block defined by Forero et al. at 2016. Visualization of sonoanatomy with US is easy, and the spread of local anesthesic agents can be easily seen under the erector spinae muscle. Thus, analgesia occurs in several dermatomes with cephalad-caudad way. It has been reported that ESPB provides lumbar analgesia at T10-12, L3. The aim of this study is to compare US-guided mTLIP block and ESPB pain management after lumbar discectomy+ surgery.

NCT ID: NCT04061759 Completed - Clinical trials for Lumbar Disc Herniation

Physiotherapy in Lumbar Disc Pathologies

Start date: September 2, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effectiveness of four physical therapy treatment approaches for lumbar region pathologies. Eighty volunteers who have back pain will be included in the study. Subjects will be randomly divided into four groups; Group 1: Soft tissue mobilisation techniques and stabilization exercises (n=20), Group 2: Kinesiotape and stabilization exercise (n=20), Group 3: Stabilization exercises (n=20), Group 4: Reflexology and stabilization exercises (n=20).

NCT ID: NCT04049812 Completed - Clinical trials for Lumbar Disc Herniation

Effectiveness of PEMF in Patients With Chronic Radicular Pain Due to Lomber Disc Herniation

Start date: March 1, 2016
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness of pulse magnetic field therapy on pain, functional status, and quality of life in patients with chronic radicular pain due to lumbar disc herniation.

NCT ID: NCT04043611 Completed - Clinical trials for Lumbar Disc Herniation

Elongation Longitudinaux Avec Decoaption Osteo-Articulaire (ELDOA) in Lumbar Disc Protrusion

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

The aim of this randomized controlled trial will be to determine the effectiveness of ELDOA for treating lumbar disc protrusion. Two randomized groups of patients with lumbar disc protrusion will be treated with conservative physical therapy and the experimental group will be given ELDOA, in addition. Both, male and female patients meeting the inclusion criteria will be included. Patients having concurrent malignancy, infection, trauma or any bony deformity will be excluded

NCT ID: NCT04042948 Completed - Clinical trials for Lumbar Spinal Stenosis

Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery

Start date: June 24, 2019
Phase: N/A
Study type: Interventional

This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the preventive use of non-steroidal anti-inflammatory drugs could decrease the possibility of fever happening when we remove the tube.