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Pentoxifylline and Lumbar Radiculopathy

Lumbar Disc Herniation Clinical Trial

Official title:
Prospective Controlled Crossover Study of the Role of Pentoxifylline in the Management of Lumbar Radiculopathy

Clinical Trial Summary

The objective of this prospective controlled crossover study is to evaluate the efficacy and safety of pentoxifylline per os (800 mg daily) in the management of lumbar radiculopathy

Clinical Trial Description

Patients with lumbar radiculopathy, are recruited from senior author clinic. After verification of inclusion and exclusion criteria, patients consenting to enter the study are given 2 sequences (order randomly assigned) of treatment: Ibuprofen 600 mg bid, with paracetamol 1000 mg tid, pregabalin 75 mg bid for 15 days with pentoxifylline and 15 days without it. Basic clinical and demographical data are noted. Lumbar MRI results are also noted. Clinical evaluation of the patient is performed and included: clinical examination (including motor exam of lower limbs); pain is assessed according to Numerical rating Scale (NRS), and relative percentage of global improvement. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03060434
Study type Interventional
Source St Joseph University, Beirut, Lebanon
Contact
Status Active, not recruiting
Phase Phase 4
Start date June 1, 2018
Completion date December 1, 2024
View Details
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