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Lumbar Degenerative Disc Disease clinical trials

View clinical trials related to Lumbar Degenerative Disc Disease.

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NCT ID: NCT05516992 Recruiting - Clinical trials for Lumbar Degenerative Disc Disease

Moderate - Severe Degenerative Disc Disease Evaluation of the Lumbar Spine

MODEL
Start date: August 19, 2022
Phase: Phase 3
Study type: Interventional

The purpose of the study is to confirm the safety and effectiveness of SB-01 For Injection in adult patients with chronic low back pain and related disability due to Lumbar Degenerative Disc Disease. The primary effectiveness hypothesis is superiority of the investigational product relative to control in terms of the percentage of subjects improving in pain-related disability.

NCT ID: NCT03974711 Completed - Clinical trials for Lumbar Degenerative Disc Disease

Rampart Duo Clinical (RaDical) Post-Market Study

RaDical
Start date: October 2, 2017
Phase:
Study type: Observational [Patient Registry]

This exempt, minimal risk, prospective, post-market, registry, multi-center, Institution Review Board (IRB) approved observational clinical evaluation was conducted at 10 centers. A total of 197 patients were enrolled. The evaluation collected data in a real-world patient population and was a data collection initiative only. No patient treatments or care were performed as a component of the protocol. All patient care received was on-label and standard of care for lateral lumbar interbody fusions. The data collected in this evaluation is intended to contribute to the body of literature for lateral lumbar interbody fusions.

NCT ID: NCT03647501 Completed - Clinical trials for Lumbar Spinal Stenosis

Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages

Start date: August 22, 2018
Phase: N/A
Study type: Interventional

The purpose of this randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo combined interbody/posterolateral lumbar fusion procedures, supplemented with pedicle screw instrumentation, using one of the following interbody cages; the Nexxt Spine Nexxt MatrixxTM 3D-printed titanium cage or the HonourTM poly-ether-ether-ketone cage.

NCT ID: NCT02529566 Enrolling by invitation - Lower Back Pain Clinical Trials

Human Autograft Mesenchymal Stem Cell Mediated Stabilization of The Degenerative Lumbar Spine

Start date: July 2013
Phase: N/A
Study type: Observational [Patient Registry]

Investigate the potential of tissue grafting that includes human mesenchymal stem cells in the repair and potential stabilization of the degenerative Lumbar disk and facet joint denovo and at the time of surgical reconstruction. Our hypothesis proposes that stabilization will help restore normal structure and function in the degenerative lumbar spine may decrease chronic low back pain associated with the biomechanical demise of the degenerative disk or facet and may improve the natural history of adjacent segment disease found after spinal surgery.

NCT ID: NCT02347410 Completed - Clinical trials for Lumbar Degenerative Disc Disease

Spineology Clinical Outcomes Trial: An IDE Investigation

SCOUT
Start date: January 22, 2015
Phase: N/A
Study type: Interventional

This study evaluated the safety and effectiveness of the Spineology Interbody Fusion System (SIFS) in an instrumented interbody lumbar fusion in subjects presenting with symptomatic single-level lumbar degenerative disc disease.

NCT ID: NCT02297256 Active, not recruiting - Clinical trials for Lumbar Degenerative Disc Disease

Prospective Study of Thoracolumbar Spinal Fusion Graft

BMAC
Start date: August 2012
Phase: N/A
Study type: Interventional

This study is a single-center, prospective randomized clinical study intended to compare and evaluate the efficacy of subjects who are treated with bone marrow aspirate concentrate (BMAC) and allograft to iliac crest bone grafts (ICBG) during posterior lumbar/lumbosacral spinal fusion.

NCT ID: NCT02139527 Terminated - Clinical trials for Lumbar Degenerative Disc Disease

CARES Lumbar Artificial Disc Registry

Start date: May 2007
Phase: Phase 4
Study type: Observational [Patient Registry]

The purpose of the registry is to assess outcomes following treatment with lumbar total disc replacement (TDR) in patients outside the clinical trial setting.

NCT ID: NCT02070484 Terminated - Clinical trials for Musculoskeletal Diseases

Human Amniotic Tissue-derived Allograft, NuCel, in Posteriolateral Lumbar Fusions for Degenerative Disc Disease

Start date: February 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect and safety of NuCel to DBX on patients undergoing posteriolateral lumbar spinal fusions for degenerative disc disease.

NCT ID: NCT01721889 Recruiting - Clinical trials for Lumbar Degenerative Disc Disease

Radiostereometric Analysis of Spine Arthrodesis

Start date: November 2012
Phase: N/A
Study type: Observational

The primary objective of this pilot study is to determine the precision of post-operative radiostereometric measurements for the assessment of lumbar spinal fusion. This study will also determine the potential for RSA as a more precise and accurate means for assessment of lumbar spinal fusion and diagnosis of pseudarthrosis.

NCT ID: NCT01689922 Terminated - Clinical trials for Lumbar Degenerative Disc Disease

The Effectiveness of Anti-Gravity Treadmill Training

Start date: June 2012
Phase: N/A
Study type: Observational

The primary objective of this study is to compare the effectiveness of standard for our practice postoperative physical therapy (PT) program to a PT program that incorporates lower body positive pressure (LBPP) treadmill training for the patients after lumbar discectomy and fusion surgeries.