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Lower Resp Tract Infection clinical trials

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NCT ID: NCT06331364 Not yet recruiting - Clinical trials for Lower Resp Tract Infection

TREATment of Lower Respiratory Tract Infection in Sri Lanka (TREAT-SL)

TREAT-SL
Start date: August 2024
Phase: N/A
Study type: Interventional

This is a stepped-wedge, cluster-randomized, two-arm, open-label, clinical trial of an electronic clinical decision support tool (eCDST) for the diagnosis and treatment of lower respiratory tract infection (LRTI) among patients at three sites in Southern Province, Sri Lanka. The primary objective of this trial is to determine the impact of an electronic clinical decision support tool (eCDST) on clinical outcomes and antibacterial prescription in subjects with LRTI in the intervention group compared to the control group. The study will enroll 765 patients ≥ 14 years of age. Medical wards will be randomized in clusters to the intervention at intervals of 3-6 months until all clusters cross over. Participants will be followed for 30 days from enrollment to record clinical outcomes and any antimicrobials prescribed.

NCT ID: NCT05534555 Not yet recruiting - Clinical trials for Lower Resp Tract Infection

Point of Care Testing Using FebriDx in Primary Care: a Mixed Methods Feasibility Study

PREFIX
Start date: October 2022
Phase: N/A
Study type: Interventional

This is a mixed-methods, multi-centre feasibility study. Formal advice and peer-review with regards to study design was sought from the Southampton Research Design Service (RDS), the NIHR CRN Wessex, and patient contributors during the development of the grant application. We will recruit up to ten GP practices, each given 20-40 FebriDx tests (300 in total). Up to four clinicians per practice will be trained to use the test. A sequential explanatory approach to data collection will be taken (21), with quantitative data analysis in stage one, followed by qualitative interviews with the study's practice participants in stage two.