MSCT Angiography in Bleeding

Lower Gastrointestinal Bleeding Clinical Trial

Official title:

Role of MSCT Angiography in Evaluation of Lower Gastrointestinal Bleeding

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03464513
• Other study ID #: Angiography
• Status: Not yet recruiting
• Phase: N/A
• First received: February 23, 2018
• Last updated: March 7, 2018
• Start date: April 1, 2018
• Est. completion date: April 1, 2020

Study information

• Verified date: March 2018
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Lower gastrointestinal bleeding occurs distal to the ligament of treitz and may involve the small bowel, colon and rectum .

Active lower gastrointestinal bleeding is a common, potentially life threatening medical presentation that can be challenging to localize and treat .

There are many diseases that may cause lower gastrointestinal bleeding, including angiodysplasia, diverticulosis, benign or malignant bowel neoplasm, inflammatory bowel disease, ischemic bowel disease, and infectious bowel disease.

Often, gastrointestinal bleeding will stop spontaneously, but in approximately 25% of patients, bleeding is massive or recurrent, requiring imaging localization and directed therapy.

Description:

Accurate and prompt diagnosis of the bleeding source is crucial because mortality can be as high as 40%if there is hemodynamic instability in patients .

Because of the length of GI tract, the multitude of pathologic processes that can result in GI bleeding, imaging plays a primary role in the diagnosis .

Multislice CT angiography (MSCTA) provides a relatively non-invasive and effective way of localising the source of bleeding, especially in patients with continuous bleeding .

MSCTA is being increasingly used because it is a widely available, non-invasive and fast diagnostic technique that allows for the visualization of the entire intestinal tract and its lesions, the identification of the vascularity and possible vascular abnormalities. In addition, this technique does not require preparation in patients with acute bleeding.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 25
• Est. completion date: April 1, 2020
• Est. primary completion date: April 1, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients presenting to assiut university hospital with active lower gastrointestinal bleeding.

Exclusion Criteria:

• Patients whom are sensitive to contrast. Pregnant women. Patients with renal insufficiency

Related Conditions & MeSH terms

• Gastrointestinal Hemorrhage
• Hemorrhage
• Lower Gastrointestinal Bleeding

Intervention

Device:
• Multislice CT Angiography
Multislice CT angiography (MSCTA) provides a relatively non-invasive and effective way of localising the source of bleeding, especially in patients with continuous bleeding.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (1)

Yoon W, Jeong YY, Shin SS, Lim HS, Song SG, Jang NG, Kim JK, Kang HK. Acute massive gastrointestinal bleeding: detection and localization with arterial phase multi-detector row helical CT. Radiology. 2006 Apr;239(1):160-7. Epub 2006 Feb 16. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	MSCTA in the evaluation of patients presenting with active lower gastrointestinal bleeding.	Multislice ct angiography	1 hour