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Lower Extremity Surgery clinical trials

View clinical trials related to Lower Extremity Surgery.

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NCT ID: NCT06301503 Completed - Clinical trials for Lower Extremity Surgery

Postoperative Quality of Recovery After Combined Lumbar Plexus-Sciatic Nerve Block (LPB-SNB)

Start date: March 9, 2024
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to evaluate the efficacy of lumbar plexus-sciatic nerve block (LPB-SNB) by comparing the postoperative quality of recovery as assessed by the Quality of Recovery-40 (QoR-40) questionnaire, in patients who received a combination of LPB-SNB versus patients who received the traditional intravenous opioid, after lower extremity orthopaedic surgeries with spinal anaesthesia. The main questions it aims to answer are: - Will there be a significant difference in QoR-40 scores between both groups? - Will the combined LPB-SNB significantly reduces opioid consumption within the first 24 hours? - Will the combined LPB-SNB significantly increases postoperative duration of analgesia? Participants will: - Receive a coded sealed opaque envelope containing their randomly allocated intervention group; first group receives a combination of lumbar plexus-sciatic nerve block, while the second group receives no block at all. This information would not be disclosed to the participants. - Receive an explanation on how to use the patient controlled analgesia (PCA) to deliver intravenous opioid, and instructions on filling in the QoR-40 questionnaire. Researchers will then compare the results between both groups to see if the combined lumbar plexus-sciatic nerve block successfully provides adequate analgesia and enhance postoperative quality of recovery after lower extremity orthopaedic surgeries.

NCT ID: NCT05201261 Not yet recruiting - Clinical trials for Lower Extremity Surgery

the Relationship Between Vertebral Body Length, Subarachnoid Space Width and Block Level

Start date: February 2022
Phase:
Study type: Observational

Spinal anesthesia technology has been widely used in various surgeries and multi-mode analgesia. Spinal ultrasound imaging has been proved to be a reliable tool for evaluating spinal parameters. Ultrasound-guided spinal puncture technology has also been skillfully applied in clinical practice. How to provide perfect nerve block effect for operation, provide good postoperative analgesia, and prevent unnecessary extensive block leading to other complications and related risks has always been the focus of anesthesiologists. Doses and the relationship between the anesthesia plane great individual differences, and previous research on the patient's own condition such as height, weight, 6 to the anesthesia plane have different results, the influence of clinical work often refer patients height adjustment of drug doses, this research attempts to evaluate ultrasound was used to assess spinal vertebral body in the plane of the length and width of subarachnoid and anesthesia.

NCT ID: NCT04518462 Completed - Bunion Clinical Trials

Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries

STRIDE
Start date: October 20, 2020
Phase: Phase 3
Study type: Interventional

This is a Phase 3, multicenter, randomized, double blinded, active controlled study in approximately 120 subjects undergoing lower extremity surgeries.

NCT ID: NCT02017145 Unknown status - Clinical trials for Surgical Site Infection

Study on the Reapplication of Chloraprep After Lower Extremity Surgery and Prior to Dressing Application

Start date: February 2014
Phase: Phase 4
Study type: Interventional

The purpose of the current work is to determine the efficacy of the re-application of surgical prep solution in decreasing surgical site bacterial contamination following lower extremity surgery. Decreasing the extent of bacterial colonization of the skin surrounding the surgical site during the initial healing phases would theoretically decrease the rate of infection in high-risk persons.

NCT ID: NCT01836419 Completed - Clinical trials for Lower Extremity Surgery

The Clinical Efficacy of Laryngeal Mask Airway in Elderly Patients: Comparison With Young Adults

Start date: December 2012
Phase: N/A
Study type: Interventional

There are some differences between elderly and young adult patients regarding the anatomy of upper airways. Elderly patients have larger upper airways than young adult patients at all pharyngeal levels as revealed by CT. Another study explained that there is a progressive descent of the larynx and epiglottis with aging, which lengthens the upper airway and possibly makes it more likely to collapse. The aim of this study is to compare the clinical efficacy of laryngeal mask airway (LMA) in elderly patients with young adults. In this study, the investigators will measure the ease of insertion, success rate of insertion, the time of insertion, oropharyngeal leak pressure, gastric leak pressure, fiberoptic position and intraoperative complications of the classic LMA.

NCT ID: NCT00997867 Completed - Post-operative Pain Clinical Trials

Perineural Catheter Insertion Distance for Continuous Peripheral Nerve Blocks

Start date: November 2009
Phase: Phase 4
Study type: Interventional

This is a research study to determine if the effects of continuous peripheral nerve blocks are influenced by the distance of insertion past the needle tip of the perineural catheter.