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Safety and Pharmacokinetics of Orally Administered Strontium L-Lactate in Healthy Adults

Osteopenia Clinical Trial

Official title:
Safety and Pharmacokinetics of Orally Administered Strontium L-Lactate in Healthy Adults

Clinical Trial Summary

No clinical trials have evaluated strontium L-lactate (SrLac), the strontium salt of the L-enantiomer of lactic acid. Therefore, this clinical study was conducted to obtain general safety and pharmacokinetic (PK) information following acute oral intakes of three doses of SrLac by healthy adults. The data provided valuable comparisons with the pharmacokinetics of other strontium salts that are in clinical use and allowed determination of the dose of SrLac that will be useful for the management of bone health.neficial for the treatment of low bone density of osteoporosis and osteopenia.

Clinical Trial Description

Purpose: The aim of this clinical study was to obtain safety and pharmacokinetic information following acute oral intakes of three ascending doses of strontium L-lactate by healthy adults.

Subjects and methods: Ten healthy men and women, mean age 43 ± 2 years, ingested one of three ascending doses of strontium L-lactate (SrLac) once per week for three weeks in succession. Fasting blood collections were performed pre-dose and 1, 2, 3, 4, 5, 6, 8 and 12 hours post-dose for determination of serum strontium at each interval. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03761979
Study type Interventional
Source BioLink Life Sciences, Inc.
Contact
Status Completed
Phase N/A
Start date March 9, 2017
Completion date July 17, 2017
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