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Periodontal Disease and Preterm Birth

Preterm Birth Clinical Trial

Official title:
Periodontal Disease, Inflammatory Markers, and Preterm Birth

Clinical Trial Summary

To determine the relationship between periodontal disease and upper genital tract inflammation in pregnancy. To determine whether certain fluid levels in the oral cavity and the vagina are associated with preterm birth or low-birth weight.

Clinical Trial Description

Patients will be enrolled in the study at their first prenatal visit after the details of the study have been discussed. Potential subjects will be presented with a questionnaire to determine eligibility for the study. The patient will be scheduled for an exam between 18-24 weeks at which time they will undergo a periodontal assessment, to determine the presence or absence of periodontal disease, a sampling of gingival crevicular fluid (GCF) and a vaginal swab collection. Periodontal disease will be determined by measuring the depth of gingival sulci, amount of periodontal attachment loss, and prevalence of gingival bleeding at six sites for each tooth present. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00582374
Study type Observational
Source University of Oklahoma
Contact
Status Withdrawn
Phase N/A
Start date March 2005
Completion date March 2009
View Details
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