Low Back Pain Clinical Trial
Official title:
Effect of Nitrous Oxide in Treating Neuropathic Pain: A Pilot Study in Chronic Low Back Pain Patients
Epidural injection will be completed under fluoroscopy and all patients will receive 1-4 mg
of Midazolam for relaxation before procedure and, if needed, 50-100 mcg of Fentanyl
intravenous (IV). Radiopaque contrast (Omnipaque 300), for confirming the epidural position
of the needle, steroids and local anesthetic agents will be used according to the physician
performing the block and will not be controlled by the study. Patients will be randomly
assigned to receive either inhaled Entonox along with the interventional block they are
scheduled for or oxygen. They will be blinded about the treatment they are receiving. Those
randomized to Entonox will inhale the gas through a mouthpiece throughout the procedure and
also continue to receive it for a total of 4 hours in the recovery. Those randomized to the
oxygen group will receive oxygen through a similar mouthpiece for the entire duration of the
procedure and recovery for 4 hours. Following completion of procedure the patient will be
transferred to recovery and monitored for 3-5 hours then discharged home with instructions.
Possible side effects will be monitored and recorded, pain score of patient will be recorded
before discharge. All the patients will receive standard instructions regarding physical
back exercises. This will be repeated for every procedure up to maximum of three blocks.
The patients will be followed during each block and over a period of 1, 3, 6 and 12 months
and on each follow-up visit will complete computerized set of questionnaires as they did
before the procedure. The patients charts will be then reviewed for one year after the
initial procedure to determine if further epidural steroid injections or surgery for the
presenting problem were required. It is anticipated that the appropriate number of patients
will be enrolled within six months of study initiation.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Supportive Care
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03916705 -
Thoraco-Lumbar Fascia Mobility
|
N/A | |
| Completed |
NCT04007302 -
Modification of the Activity of the Prefrontal Cortex by Virtual Distraction in the Lumbago
|
N/A | |
| Completed |
NCT03273114 -
Cognitive Functional Therapy (CFT) Compared With Core Training Exercise and Manual Therapy (CORE-MT) in Patients With Chronic Low Back Pain
|
N/A | |
| Recruiting |
NCT03600207 -
The Effect of Diaphragm Muscle Training on Chronic Low Back Pain
|
N/A | |
| Completed |
NCT04284982 -
Periodized Resistance Training for Persistent Non-specific Low Back Pain
|
N/A | |
| Recruiting |
NCT05600543 -
Evaluation of the Effect of Lumbar Belt on Spinal Mobility in Subjects With and Without Low Back Pain
|
N/A | |
| Withdrawn |
NCT05410366 -
Safe Harbors in Emergency Medicine, Specific Aim 3
|
||
| Completed |
NCT03673436 -
Effect of Lumbar Spinal Fusion Predicted by Physiotherapists
|
||
| Completed |
NCT02546466 -
Effects of Functional Taping on Static Postural Control in Patients With Non-specific Chronic Low Back Pain
|
N/A | |
| Completed |
NCT00983385 -
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics
|
Phase 3 | |
| Recruiting |
NCT05156242 -
Corticospinal and Motor Behavior Responses After Physical Therapy Intervention in Patients With Chronic Low Back Pain.
|
N/A | |
| Recruiting |
NCT04673773 -
MY RELIEF- Evidence Based Information to Support People Aged 55+ Years Living and Working With Persistent Low-back Pain.
|
N/A | |
| Completed |
NCT06049277 -
Mulligan Technique Versus McKenzie Extension Exercise Chronic Unilateral Radicular Low Back Pain
|
N/A | |
| Completed |
NCT06049251 -
ELDOA Technique Versus Lumbar SNAGS With Motor Control Exercises
|
N/A | |
| Completed |
NCT04980469 -
A Study to Explore the Effect of Vitex Negundo and Zingiber Officinale on Non-specific Chronic Low Back Pain Due to Sedentary Lifestyle
|
N/A | |
| Completed |
NCT04055545 -
High Intensity Interval Training VS Moderate Intensity Continuous Training in Chronic Low Back Pain Subjects
|
N/A | |
| Recruiting |
NCT05944354 -
Wearable Spine Health System for Military Readiness
|
||
| Recruiting |
NCT05552248 -
Assessment of the Safety and Performance of a Lumbar Belt
|
||
| Completed |
NCT05801588 -
Participating in T'ai Chi to Reduce Back Pain and Improve Quality of Life
|
N/A | |
| Completed |
NCT05811143 -
Examining the Effects of Dorsal Column Stimulation on Pain From Lumbar Spinal Stenosis Related to Epidural Lipomatosis.
|