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Low Back Pain clinical trials

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NCT ID: NCT04255199 Active, not recruiting - Low Back Pain Clinical Trials

Watchful Waiting as a Strategy for Reducing Low-value Spinal Imaging

Start date: October 21, 2020
Phase: N/A
Study type: Interventional

The investigators will learn from the study whether actors playing the roles of patients (standardized patients) can help primary care and urgent care clinicians develop skill in offering watchful waiting to patients with acute low back pain as a means of averting low-value spinal imaging. Using patient and physician feedback, this study will refine and evaluate -- in a controlled experiment -- a simulated standardized patient intervention to enhance primary care physician use of watchful waiting when patients request low-value spinal imaging. The long-term goal of this study is to discover communication strategies primary care physicians can use to avert costly, potentially harmful testing while maintaining the patient-doctor relationship.

NCT ID: NCT04246281 Active, not recruiting - Low Back Pain Clinical Trials

The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain

Start date: June 17, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to compare standard of care treatments for back pain to electrical stimulation. Stimulation is delivering small amounts of electricity to the nerves in your low back. This study will use a device called the SPRINT Peripheral Nerve Stimulation (PNS) System. The device is cleared by the FDA for up to 60 days of use for the relief of chronic or acute pain (including back pain)

NCT ID: NCT04238676 Active, not recruiting - Clinical trials for Chronic Low-back Pain

Persica 002 Phase 1b PP353 vs Placebo in the Treatment of Low Back Pain

Start date: January 20, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

A Phase 1b study to investigate the efficacy of PP353 compared to placebo in the treatment of chronic low back pain associated with bone oedema.

NCT ID: NCT04236804 Active, not recruiting - Clinical trials for Chronic Low-back Pain

Implementing TMC-CP01 Treatment Based on the Virtual Autonomic Neuromodulation Induced Systemic Healing System in Reducing Pain and Opioid Requirement in Subjects Suffering From Chronic Low Back Pain

VANISH
Start date: June 17, 2020
Phase: N/A
Study type: Interventional

The program, called TMC-CP01, will use a combination of virtual reality, biofeedback, and psychological exercises to manage pain associated with Chronic Low Back Pain. Chronic pain affects an estimated 100 million Americans, around one-third of the U.S. population. One of the most prevalent conditions under chronic pain is Chronic Low Back Pain (CLBP). About 27% of chronic pain patients experience CLBP. It is the leading cause of disability in the world and 31 million Americans suffer from CLBP. The most common analgesic tool for pain patients, especially for LBP patients, is opioids. However, opioid users are subject to drug tolerance and physical dependence, which decreases efficacy and increases risk of complication. Long-term users often require doses up to ten times their original dose to achieve equivalent analgesia and, after months of exposure, patients' risk of addiction increases. This project aims to introduce a digital intervention to standard CLBP management with a virtual reality-enabled pain management system that will improve pain management and decrease daily dosages of opioids.

NCT ID: NCT04141098 Active, not recruiting - Clinical trials for Degenerative Disc Disease

Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nuclectomy

LOPAIN1
Start date: October 10, 2019
Phase: N/A
Study type: Interventional

This study will be a prospective, open-label, multi-center study that will collect safety data for the minimally invasive PerQdisc Nucleus Replacement Device deployed to reduce chronic low back pain.

NCT ID: NCT04129034 Active, not recruiting - Clinical trials for Facet Syndrome of Lumbar Spine

Safety and Initial Feasibility of Using the Neurolyser XR Device for the Treatment of Axial Chronic Low Back Pain

Start date: September 24, 2019
Phase: N/A
Study type: Interventional

Single arm pilot study to evaluate the safety and initial feasibility of the Neurolyser XR, a high intensity focused ultrasound device, for non-invasive treatment of axial chronic low back pain

NCT ID: NCT04103970 Active, not recruiting - Low Back Pain Clinical Trials

The Effect of Graded Activity and Pain Education (GAPE) for Patients Early After Lumbar Spinal Fusion

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Background An increasing number of patients with chronic low back pain (CLBP) undergo lumbar spinal fusion (LSF). Unfortunately, a substantial part of the patients still has persistent pain, functional disability and poor quality of life after surgery. Research in the field of rehabilitation after LSF call for high quality research to focus on active approaches which incorporate an early bio-psycho-social focus. A focus which include the patient's context, experiences and thoughts even more in the clinical decision making. The primary objective of this trial is to examine the effect of an early active rehabilitation-intervention consisting of Graded Activity and Pain Education (GAPE) on sedentary behavior in a population of patients undergoing LSF. The secondary objectives are to examine the effect of GAPE on disability, pain, fear of move-ment, self-efficacy for exercise and health related quality of life. Methods: The study is a randomized controlled trial planned to include 144 patients after LSF caused by degeneration of the lumbar spine (including spondylolisthesis). The patients will be randomly assigned to receive either usual care or usual care plus GAPE. GAPE consists of 9 individual sessions, with an overall purpose to influence the patient beliefs and thoughts about movement and pain towards increased self-efficacy for exercise and decreased fear of movement. A physiotherapist will in close collaboration with the patient plan GAPE based on an in-depth pain-anamnesis, individually set functional goals and observations of the patients in their homes. The primary outcome will be "reduction in sedentary behavior" measured by an accelerometer. Sec-ondary outcome will include disability, pain, fear of movement, self-efficacy for exercise and quality of life. Data will be collected at baseline (pre-surgery), and at 3, 6- and 12-months post-surgery.

NCT ID: NCT04087291 Active, not recruiting - Low Back Pain Clinical Trials

Veterans Response to Dosage in Chiropractic Therapy

VERDICT
Start date: February 23, 2021
Phase: N/A
Study type: Interventional

This study evaluates how Veterans with chronic low back pain (cLBP) respond to varying doses of chiropractic therapy and how health services utilization are impacted as a result. There are 2 phases in this study. In Phase 1, half of participants will receive a low dose (1-5 visits) of chiropractic care for 10 weeks, while the other half will receive a higher dose (8-12 visits) for 10 weeks. At the end of Phase 1, participants in each group will be randomized again to receive either chronic chiropractic pain management (CCPM) (1 scheduled chiropractic visit per month x 10 months) or no CCPM for 10 months.

NCT ID: NCT04034186 Active, not recruiting - Low Back Pain Clinical Trials

The Quality of Physiotherapy in Low Back Pain Patients in Central Finland

Start date: December 2014
Phase:
Study type: Observational

Chronic low back pain is one of the most common musculoskeletal disorders. In the Finnish Health 2000 survey the incidence of low back pain was 10% in men and 11% in women. Several evidence-based rehabilitation guidelines recommend exercise therapy treatment of chronic back pain. However, there are no studies in chronic low back pain patients concerning the assessment of the content and quality of exercise modalities adviced in clinical practise. The aim of this study is to investigate the content and quality of physiotherapy management and advise in chronic low back pain patients in Central Finland.

NCT ID: NCT04004156 Active, not recruiting - Clinical trials for Degenerative Disc Disease

Safety Study for An Artificial Disc Replacement to Treat Chronic Low Back Pain

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

This study will be a prospective, open-label, multi-center study that will collect safety data for the minimally invasive PerQdisc Nucleus Replacement Device deployed to reduce chronic low back pain.