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Low Back Pain clinical trials

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NCT ID: NCT03564418 Recruiting - Low Back Pain Clinical Trials

Ultrasound-Guided Thermocoagulation of Medial Nerve Branch in Lumbar Facet Joints Pain.

Start date: January 2, 2018
Phase: N/A
Study type: Interventional

We propose here to evaluate the precision of lumbar thermocoagulation performed under a transverse ultrasound approach by performing a fluoroscopic control once the needle in the desired position. The effectiveness of the technique will be assessed by measuring different pain and disability scores at six weeks post-thermocoagulation: the Visual analogue pain Scale score (VAS) and the Oswestry disability score (ODI) will be collected, compared to that of the conventional fluoroscopic technique.

NCT ID: NCT03509376 Recruiting - Diastasis Recti Clinical Trials

Operative Correction of Rectus Muscle Diastasis (ARD): the Effect on Low Back Pain and Movement Control

RmB
Start date: April 1, 2018
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial comparing two ADR repair methods: nylon suturing and nylon suture with mesh enforcement. The ADR correction is performed simultaneously with abdominoplasty/ modified skin reduction abdominoplasty.

NCT ID: NCT03475095 Recruiting - Low Back Pain Clinical Trials

Motor Control Mechanisms by CNS of Tuina in Patients With Lumbar Disk Herniation

Start date: March 10, 2018
Phase: N/A
Study type: Interventional

Lumbar disk herniation (LDH)is a prevalent health problem around the world. It can cause symptoms of low back pain, numbness or weakness.The understanding of low back pain in traditional Chinese medicine(TCM) theory"unbalanced bones and muscles"that is consistent with the description of modern medicine on LDH function pathology. Tuina is one of Diagnosis and treatment methods in TCM which has been used as a noninvasive treatment of LDH. However, the mechanism of Tuina therapy in LDH is still unclear.The purpose of this study is to establish a platform of the therapeutic effect and mechanical effect of LDH in the treatment of LDH,explore the characteristics of Tuina by the motor control in lumbar CNS,observe the patterns and regularities in the function of related brain regionin of patients with acute or chronic LDH and reveal the mechanism of Tuina of improving the control of lumbar spine CNS movement.

NCT ID: NCT03463200 Recruiting - Low Back Pain Clinical Trials

KT on Low Back Pain Patients

Start date: March 5, 2018
Phase: N/A
Study type: Interventional

This study aim evaluates the effect of Kinesio Taping (KT) on back muscle fatigue of low back pain patients, analysing the electromyography activity of longissimus muscle (median frequency) and the sustained time during a fatigue test (Ito test).

NCT ID: NCT03453775 Recruiting - Low Back Pain Clinical Trials

Ultrasound-guided Lumbar Periradicular Injection: a Non Irradiating Infiltration Technique

Start date: February 27, 2018
Phase: N/A
Study type: Interventional

We propose here to evaluate the precision of lumbar periradicular infiltration performed under a transverse ultrasound approach by performing a fluoroscopic control once the needle in the desired position. The effectiveness of the technique will be assessed by measuring different pain and disability scores at four weeks post-infiltration: the Visual analogue pain Scale score, the DN4 score, and the Oswestry disability score (ODI); The decrease in irradiation received will be collected, compared to that of the conventional fluoroscopic technique.

NCT ID: NCT03406624 Recruiting - Low Back Pain Clinical Trials

Epigenetic and Molecular Biomarkers in Chronic Low Back Pain and Modic Changes

Start date: January 29, 2018
Phase:
Study type: Observational

In the present study the investigators aim to examine the presence of bacteria in the disc and Modic Changes (MCs) (bone). A prospective study with 1-year follow-up of two patient populations undergoing elective spinal surgery (spinal fusion or disc herniation surgery) will be conducted. Patients previously operated on at index level will also be included, and evaluated as sub-groups. The following tissues are collected: dermis, sub-fascial tissue, nucleus pulposus, annulus fibrosus, and endplates. Endplate biopsies are only performed in patients undergoing fusion surgery. All tissue samples undergoing culturing should be processed within 4 hours of sampling. The time for sampling and culture processing are noted for each sample.In short, 1 mL enrichment broth (Brain Heart Infusion, BHI) is added to each tissue sample and further homogenized using sterile beads or a mortar. In addition, a control sample containing only enrichment broth is included. The control sample also undergoes the homogenization step. Each sample is plated onto three agar plates: blood and chocolate for aerobic culturing and anaerobic medium (HM0 or FAA) anaerobic culturing. The blood and chocolate agar plates and the enrichment broth are incubated in 35oC (5% CO2) and the anaerobic plates are incubated anaerobically for a total of 14 days. On day 3 and 7, the enrichment broth is plated onto a chocolate and an anaerobic agar for aerobic and anaerobic incubation respectively. Aerobic plates are read every 1-2 days and the anaerobic plates are read every 2-3 days. All growth is identified and recorded. Colonies considered relevant are frozen at -80oC. The pre-specification of microbiological results; significant growth, no growth and probable contamination (< 5 single colonies on primary plate and no growth from enrichement broth or no growth on primary plate, but growth from enrichement broth). Main endpoint for bacteriology is significant growth or no growth. A prespecification of PCR results in the probable contamination group seems to be premature, due to high risk of contamination. We will perform sensitivity analysis as the samples are analyzed, and PCR and histology will be used in combination to determine if a probable contamination should be considered in the significant growth group or in the no growth group. In addition to a pre-specified evaluation of growth or not, microbiologists and the pathologist are blinded to the knowledge of case or control. The clinicians are blinded to the results of aerob/anaerobe cultivation, PCR and histological report. Hence, the decision of no bacterial growth, probable contamination or significant growth cannot be influenced by information of case or control. Blood-samples are collected to characterize gene expression patterns and related markers to gain insight into molecular mechanisms that may be important for low back pain (LBP) and the development of MCs

NCT ID: NCT03387930 Recruiting - Low Back Pain Clinical Trials

The Role of Lumbar Multifidus Characteristics in the Development of Low Back Pain

Start date: August 1, 2017
Phase:
Study type: Observational

Low back pain (LBP) is a severe epidemic in the world. Despite its high prevalence, 90% of the cases have no identifiable cause. Approximately 44% of them experience recurrent LBP within one year and 10% of them develop chronic LBP that lasts for three months or more. Mechanically, the lumbar spine is unstable and requires spinal muscle to maintain spinal stability and to prevent injuries. Lumbar multifidus (LM) muscle is thought to be the major spinal stabilizer responsible for spinal stability and spinal proprioception. Prior studies have revealed that increased fat infiltration, atrophy or activation deficits of LM in patients with LBP as compared to asymptomatic individuals. Unfortunately, inconsistent findings have also been reported. Although prior research attempted to determine if abnormal LM characteristics can inform clinical decision-making, their results are limited because they only investigated a single LM characteristic at a time, which might not reflect the actual LM condition. Further, many studies adopted cross-sectional design that could not reveal the casual relations between abnormal LM characteristics and LBP. As such, the current study aims to identify specific LM characteristics that can predict new episode of LBP in asymptomatic individuals, and recurrent/chronic LBP in individuals with LBP at baseline.

NCT ID: NCT03376724 Recruiting - Clinical trials for Chronic Low Back Pain

Functional Exercises for Chronic Low Back Pain

Start date: November 10, 2017
Phase: N/A
Study type: Interventional

Non-specific low back pain is a common condition. Exercise is effective treatment for chronic low back pain. We hypothesized the functional exercise group will present pain reduction and functional improvement. The purpose of this study is investigated the effectiveness of an functional exercise program for people with nonspecific chronic low back pain. Patients will be randomly divided into 2 groups: control group (minimal intervention - mini back school and analgesic) and group will receive a functional exercise protocol associated with minimal intervention.

NCT ID: NCT03368521 Recruiting - Low Back Pain Clinical Trials

The Benefit of Structured Triage of Patients in the Primary Health Care Seeking Care for Low Back Pain

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

This study aims to investigate if a low back pain screening tool is helpful for the caregivers to direct the rehabilitation in a more efficient way, at an earlier stage. Primary Health care centers in the municipality of Halmstad, Sweden will be enrolled to participate in the study as either "Control" or "intervention". The primary Health care centers who are enrolled taking part in the intervention, will use the provided screening tool when taking care of patients seeking care for low back pain. Scorings from the screening tool will "label" the patients as one of Three pre-defined risk levels. The caregiver will then use the provided risk level when deciding how to proceed the rehabilitation. Based on the risk level identified, the patient is directed to one of three levels of treatments - including simple advice; physiotherapy; or multimodal rehabilitation. The screening tool is used as a complement to the examination, allowing the physiotherapist /GP to decide how to proceed with rehabilitation using the back screening tool, together with Clinical examinations. The Control Group consists of patients recruited when seeking care for back pain at a Primary Health Care service who has been randomly selected as "Control". The care givers at the Control primary Health care will conduct as usual, not using the back pain screening tool in their Clinical examinations.

NCT ID: NCT03353142 Recruiting - Clinical trials for Chronic Low Back Pain

The Effects Of Equal Breathing On Pain Pressure Thresholds

EB-Pain
Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Recent research has found that there is moderate evidence for the use of breathing exercises for treating chronic, non-specific low back pain. Researchers have found that there were significant improvements in pain and quality of life in those suffering with low back pain who completed a breathing program intervention. Researchers also found that healthy individuals had higher pain thresholds and tolerance following deep and slow breathing exercises. There are numerous formats of breathing interventions, some interventions that have been used with individuals with chronic, non-specific low back pain include: deep breathing, yoga breathing, resisted inspiration, and breathe holding. There is moderate evidence to suggest the use of these interventions for managing chronic low back pain Another common breathing format is Equal-Ratio Breathing. This format requires an individual to inhale and exhale with the same duration while gradually increasing the duration of both. This breathing format can be easier for patients to perform given the simplicity of the equal inhalation to exhalation ratio. This research is being done because Equal-Ratio Breathing has yet to be studied in individuals with chronic low back pain.