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Low Back Pain clinical trials

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NCT ID: NCT05100381 Recruiting - Low Back Pain Clinical Trials

Effectiveness of Dry Needling in Patients With Chronic Nonspecific Low Back Pain

Start date: July 25, 2022
Phase: N/A
Study type: Interventional

Low back pain is a major health problem that affects psychosocial, economical, functional and physical aspects of the patients' life. The aim of this study will be to investigate the effectiveness of dry needling on pain, functional disability, postural control and pain pressure threshold in patients with chronic nonspecific low back pain using a randomized controlled trial design. Patients with chronic nonspecific low back pain will be randomly divided into two groups: Experimental group (dry needling and routine physical therapy) and control group (sham dry needling and routine physical therapy). Primary outcomes will be pain intensity and functional disability. Postural control and pain pressure threshold will be considered as secondary outcomes.

NCT ID: NCT05092828 Recruiting - Low Back Pain Clinical Trials

Does Intrathecal Morphine Affect Outcomes in Spine Deformity Surgery

Start date: December 1, 2021
Phase: Phase 4
Study type: Interventional

This study aims to compare the effects of intrathecal morphine to traditional pain management strategies on post-operative recovery for deformity surgery.

NCT ID: NCT05090553 Recruiting - Clinical trials for Degenerative Disc Disease

Protocol for an Analytical Study With Microbiological, Phenotypic, Genotypic and Multiomics Techniques

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

The study aims to identify metabolites present in intervertebral discs colonized by C. acnes from patients with low back pain and degenerative disc disease, correlating them with their clinical, radiological and demographic profiles.

NCT ID: NCT05085782 Recruiting - Fibromyalgia Clinical Trials

Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain

Start date: February 7, 2022
Phase: Phase 2
Study type: Interventional

The primary aim of this study is to document the feasibility and acceptability of an intervention consisting of pain neuroscience education and reconsolidation therapy with propranolol in adults suffering from chronic pain (chronic low back pain or fibromyalgia). The secondary aim of the study is to estimate the effect size of the intervention on pain and function one month post-intervention, and to obtain data for sample-size calculation for a subsequent randomized controlled trial.

NCT ID: NCT05080452 Recruiting - Abdominal Pain Clinical Trials

Visualizing ACNES and LUCNES With DIRT

Start date: January 1, 2022
Phase:
Study type: Observational

Anterior cutaneous nerve entrapment syndrome (ACNES) is caused by nerve entrapment in the abdominal wall. Recently de Weerd and Weum have suggested lumbar cutaneous nerve entrapment syndrome (LUCNES) as a name for a similar condition in the lower back. DIRT can potentially be used to identify the locations of perforators, thereby also indirectly identifying the location of nerve entrapment in ACNES and LUCNES, when a point of maximal pain corresponds to a hot spot. This study evaluates the location of hot spots on DIRT in relation to tender points and perforators visualized with CT angiography and color Doppler. In the ACNES patients, DIRT performed with a low-cost smartphone thermal camera will be compared to DIRT with a professional thermal camera to evaluate the usefulness of low-cost equipment to visualize the point of nerve entrapment.

NCT ID: NCT05066334 Recruiting - Clinical trials for Chronic Low-back Pain

Efficacy of Intradiscal Injection of Autologous BM-MSC in Subjects With Chronic LBP Due to Multilevel Lumbar IDD

DREAM
Start date: March 22, 2021
Phase: Phase 2
Study type: Interventional

DREAM is a phase II B efficacy monocentric, prospective, randomized, controlled double blinded trial, comparing intra-discal autologous adult bone marrow mesenchymal stem cells (BM-MSC) therapy and sham treated controls in subjects with chronic (> 6 months) Low Back Pain (LBP) due to lumbar multilevel (max. 3 levels) intervertebral disc degeneration (IDD) unresponsive to conventional therapy. Duration of the recruitment period has been estimated to be 12 months. The efficacy of intradiscal injection of autologous BM-MSC in reducing chronic LBP due to multilevel lumbar IDD will be evaluated after 24 months in terms of pain relief (VAS), functionality (ODI) and quality of life (SF36).

NCT ID: NCT05059496 Recruiting - Low Back Pain Clinical Trials

Effects of Hamstring Stretching Using Pressure Biofeedback Unit in Patients With Low Back Pain.

Start date: October 13, 2020
Phase: N/A
Study type: Interventional

To determine the effects of Hamstring stretching using a pressure Biofeedback unit on muscle length, pain, and functional status in patients with low back pain.

NCT ID: NCT05049772 Recruiting - Motor Imagery Clinical Trials

Telerehabilitation-based Motor Imagery in Nonspecific Low Back Pain

Start date: October 8, 2022
Phase: N/A
Study type: Interventional

Low back pain is a common problem in society and causes loss of workforce. Its lifetime prevalence reaches 80% and annual hospital admission rates in the adult population reach 15%.Most studies on motor imagery suggested the effects of motor imagery are related to neuroplastic changes in the brain. Studies have shown that similar brain regions are activated during motor imagery and real movement. However, the level of evidence about the effect of motor imagery on autonomic functions is limited. Today, interest in telerehabilitation has increased due to the Covid-19 pandemic. The aim of this study is to examine the effects of telerehabilitation-based motor imagery training in patients with non-specific low back pain.

NCT ID: NCT05047614 Recruiting - Orthopedic Disorder Clinical Trials

Effects of Lumbar Repositioning Feedback and Transversus Abdominis Training on Lumbar Propricption in Patients With Chronic Mechanical Low Back Pain

Start date: April 19, 2020
Phase: N/A
Study type: Interventional

This study is conducted to answer the following question: What is the effect of lumbar repositioning feedback and transverses abdominis training on lumbar proprioception in patients with chronic mechanical low back pain?

NCT ID: NCT05047562 Recruiting - Low Back Pain Clinical Trials

Effect of Pilates and Segmental Stabilization in Elderly People With Low Back Pain

Start date: June 13, 2019
Phase: N/A
Study type: Interventional

INTRODUCTION: Low back pain is an important health condition with great consequences from the socioeconomic point of view and is associated with high costs for the health system, absenteeism at work and reduced functional performance. It is considered one of the most relevant health problems in the elderly, with point prevalence estimates higher than for other musculoskeletal conditions. It can be defined as any pain between the last ribs and the lower gluteal folds, with or without pain in the lower limbs, manifesting itself acutely, subacutely or chronically. OBJECTIVE: To compare the effect of the Pilates method versus segmental stabilization in elderly people with chronic low back pain. METHOD: 60 elderly people with chronic low back pain will participate in the study and will be randomized into two groups: Pilates Group (GP) and Segmental Stabilization Group (SG). The two treatments will have 16 individual sessions, twice a week. Pain will be assessed using the visual analogue pain scale; functional disability, using the Oswestry disability index; excessive fear of movement and physical activity, by the Tampa scale of kinesiophobia; level of confidence in the balance for specific activities, by the ABC scale and; activation of the transversus abdominis muscle by pressure biofeedback. Individuals will be evaluated in four moments: before the first session, after the last session, three and six months after the end of the treatment to verify the effects in the medium term. Patient allocation and assessments will be performed by a blind examiner. Data will be analyzed using the ANOVA procedure and Tukey's Multiple Comparison test. The significance level will be 5%. A hipótese deste estudo é que o grupo que realiza exercícios de Pilates obtém ganhos mais obtem que o grupo que realiza exercícios de estabilização segmentar em todas as variáveis ao final do tratamento.