Clinical Trials Logo
  1. Home
  2. Low Back Pain, Recurrent
  3. NCT06306742
  4. Details
NCT06306742 Clinical Trial

Open-label Placebo in Manual Therapy

Low Back Pain, Recurrent Clinical Trial

Official title:
Open-label Placebo in Manual Therapies: a Pilot Study.

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06306742
Other study ID # ct9874
Secondary ID
Status Recruiting
Phase Phase 2
First received
Last updated
Start date February 26, 2024
Est. completion date June 2026

Study information
Verified date March 2024
Source Studio Osteopatico Busto Arsizio
Contact Carolina Lavazza
Phone +39 02 96701013
Email carolina.lavazza@docenti.aimoedu.it
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

to investigate the effects of placebo in patients affected by low-back pain.

Recruitment information / eligibility
Status Recruiting
Enrollment 30
Est. completion date June 2026
Est. primary completion date December 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: Adult patients (+18 years) who complain of chronic non-specific low back pain for at least 3 months with or without pain exacerbations at the time of recruitment, will be included. -Patients will need to have a diagnosis of low back pain made by a physician Exclusion Criteria: - pathologies such as ankylosing spondylitis, infections, fractures, tumors or metastases. - Pregnant women - patients with previous spinal surgery or undergoing cortisone therapy in the 6 months prior to the trial - diseases that may affect the interpretation of results such as fibromyalgia - patients currently being treated by other specialists or other manual therapists

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Open-label placebo
Light pressure manual therapy
• Osteopathic manipulative treatment
Manual therapy

Locations
Country Name City State
Italy CTFO Saronno Varese

Sponsors (1)
Lead Sponsor Collaborator
Studio Osteopatico Busto Arsizio

Country where clinical trial is conducted

Italy, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in Numeric Rating Scale a verbal determination of a pain level on a scale from 0 to 10, in which 0 represents no pain and 10 represents excruciating pain. Change from baseline of numeric rating scale at week 2, 4 and 8.
Primary Adverse effects Number and types of adverse effects occurred after intervention through study completion (8 weeks)
Secondary Change in measures of Von Frey filaments Changes in pressure measures from baseline at week 2,4 and 8.
Secondary Changes in algometer measurements Changes in pressure with algometer from baseline at week 2, 4 and 8
See also
  Status Clinical Trial Phase
Completed NCT03852667 - The Effect of Secondary Prevention in Patients With Recurrent Low Back Pain N/A
Completed NCT02235207 - Effectiveness of Fustra—Exercise Program in Neck and Low Back Pain N/A
Terminated NCT00973024 - A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Low Back Pain Phase 2
Active, not recruiting NCT00908102 - Managing Non-acute Low Back Symptoms in Occupational Health: Two Trials N/A
Completed NCT04979403 - Efficacy of Two Physiotherapy's Approaches in Chronic Low Back Pain: Is Addressing Psychosocial Factors Beneficial? N/A
Completed NCT05223946 - Treatment and Companion Diagnostics of Lower Back Pain Using SCENAR and Passive Medical Radiometry (MWR) N/A
Recruiting NCT03680287 - Effects of Sleep Disruption on Drug Response Phase 2
Not yet recruiting NCT04542798 - CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting N/A
Recruiting NCT05840302 - Effectiveness of a Pain Neuroscience Education Programme on Physical Activity in Patients With Chronic Low Back Pain N/A
Completed NCT06143319 - Structural White and Gray Matter Correlates of Impaired Muscle Control and Deficient Pain Processing
Completed NCT00361270 - Treatment of Veterans With Chronic Low Back Pain N/A
Completed NCT03328689 - Back2LiveWell: Community Based Prevention of Back Pain Flare-ups N/A
Recruiting NCT05350254 - Implementation of the MAINTAIN Instrument for Patients With Dysfunctional Spinal Pain N/A
Completed NCT04592094 - Evaluation of Performances and Safety of the Medical Device Blueback® Physio for Patients With Chronic Low Back Pain N/A
Completed NCT04436003 - GDS Muscle and Articulation Chain Treatment for Chronic LBP and Spinal Stenosis N/A
Completed NCT04943640 - The Additional Effect of Different Taping Applications in Patients With Lumbar Radiculopathy N/A
Completed NCT05682287 - The Effect of Radiofrequency of 448 kHz on Pain and Function N/A
Recruiting NCT04074798 - Hyperventilation in Patients With Chronic Low Back Pain N/A
Recruiting NCT03984864 - Preference, Exercise Therapy Adherence and Efficacy Low Back Pain N/A
Recruiting NCT05706103 - Exercise Therapy for Recurrent Low Back Pain: Unraveling the Puzzle of Peripheral Muscle and Central Brain Changes N/A