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Comparing the Efficacy of Surgery Staging and Image Staging of Locally Advanced Cervical Cancer

Locally Advanced Cervical Cancer Clinical Trial

Official title:
Non-randomized Concurrent Controlled Trial of Surgery Staging or Image Staging of Locally Advanced Cervical Cancer

Clinical Trial Summary

The study is a domestic multicenter, prospective, non-randomized controlled concurrent trial. It will be assessed whether surgery staging on locally advanced cervical cancer is superior to image staging for improving progression-free survival and overall survival.

Clinical Trial Description

All eligible patients will be divided into the following two treatment groups nonrandomly. Image staging group: standard chemoradiation (Pelvic EBRT/Extended-field EBRT + concurrent platinum-containing chemotherapy+brachytherapy). Surgery staging group: open/minimally invasive para-aortic lymph node dissection followed by concurrent chemoradiation. (Level of lymph node dissection: At least the inferior mesenteric artery. Chemoradiation will be conducted within 28 days postoperatively.) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05378087
Study type Interventional
Source Chongqing University Cancer Hospital
Contact Dongling Zou, M.D.
Phone 13657690699
Email cqzl_zdl@163.com
Status Recruiting
Phase N/A
Start date June 27, 2022
Completion date December 31, 2032
View Details
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