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Study of Durvalumab With Chemoradiotherapy for Women With Locally Advanced Cervical Cancer (CALLA) — CALLA  

Locally Advanced Cervical Cancer Clinical Trial

Official title:
A Phase III, Randomized, Multi-Center, Double-Blind, Global Study to Determine the Efficacy and Safety of Durvalumab in Combination With and Following Chemoradiotherapy Compared to Chemoradiotherapy Alone for Treatment in Women With Locally Advanced Cervical Cancer

Clinical Trial Summary

This is a randomized, multi-center, double-blind, placebo-controlled, global, Phase III study to determine the efficacy and safety of durvalumab + Chemoradiotherapy versus Chemoradiotherapy alone as treatment in Women With Locally Advanced Cervical Cancer

Clinical Trial Description

Women will be randomized in a 1:1 ratio to receive treatment with concurrent durvalumab + standard of care (SoC) or Placebo + Soc, followed by durvalumab/placebo maintenance for 24 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03830866
Study type Interventional
Source AstraZeneca
Contact
Status Completed
Phase Phase 3
Start date February 15, 2019
Completion date July 3, 2023
View Details
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