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Laparoscopic Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy

Liver Tumor Clinical Trial

Official title:
Laparoscopic Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy

Clinical Trial Summary

The purpose of this research is evaluate the results with laparoscopic ALPPS procedure in a single center. The validity, feasibility and limitations were assessed objectively through our clinical prospective study.The investigators expect laparoscopic ALPPS is safe, effective and feasible.

Clinical Trial Description

Background: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a breakthrough in the field of hepatobiliary surgery in recent years，which stimulates the remnant liver volume(RLV) grew by 74%-87.2% in 9 to 13 days。The published literature reported that the two stages of ALPPS are the conventional laparotomy surgery，Patients need to undergo the injury of two open operations in a short time. The incidence of postoperative complications and mortality rate is as high as 53% -73% and 12%-27%.The aim of this study was to evaluate the results with laparoscopic ALPPS procedure in a single center, with special emphasis in validity, feasibility and limitations. Results: Clinical data include: operation time, intraoperative blood loss, volume of blood transfusion, complications and mortality, postoperative liver function, long-term curative effect and survival time were collected and analysed. Statistical method:groups t-test ，univariate/multivariate analysis, logistic regression analysis, mixed linear regression, Cox survival analysis ，Kaplan-Meier survival analysis，Log-rank survival curves were used. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02203409
Study type Observational
Source Southwest Hospital, China
Contact Shuguo Zheng
Phone 86-13508308676
Email shuguozh@gmail.com
Status Recruiting
Phase
Start date July 2014
Completion date August 2022
View Details
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