Investigation of the Effects of Motor Cognitive Dual Task Exercises on Cognitive Function, Balance and Functional Capacity in Patients Who Have Undergone Liver Transplantation.

Liver Transplantation Clinical Trial

Official title:

Physiotherapy and Rehabilitation Doctoral Thesis Work

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05909371
• Other study ID #: Hasankalyoncüüniversityilker
• Status: Recruiting
• Phase: N/A
• Start date: February 1, 2023
• Est. completion date: March 1, 2024

Study information

• Verified date: January 2024
• Source: Hasan Kalyoncu University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Liver transplantation is a life-saving treatment of choice for patients with acute or chronic liver failure. Liver transplantation is performed with a graft taken from a living donor or cadaver in patients with end-stage liver failure or who develop various complications regardless of the stage of the disease.In liver diseases, cognitive problems occur as well as physical problems. It has been observed that in some liver diseases, including hepatitis C, Wilson's disease, primary biliary cirrhosis, cognitive dysfunction that negatively affects the quality of life of patients, from mild cognitive problems to hepatic encephalopathy.

Our study will be carried out in Malatya İnönü University Turgut Özal Medical Center Liver Transplant Institute Hospital in order to investigate the effects of motor-cognitive dual-task exercises on cognitive function, balance and functional capacity in liver transplant patients.It will be divided into 2 groups as classical physiotherapy and motor-cognitive exercise. Classical physiotherapy and motor-cognitive exercise programs will be applied to the groups in accordance with the clinical characteristics of the individuals, tolerable, and in a standardized manner specific to the individuals. Evaluations will be made on the first day and at the end of the twenty-fourth session while the patient is in the service before starting the treatment.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 32
• Est. completion date: March 1, 2024
• Est. primary completion date: November 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 50 Years to 80 Years

Eligibility

Inclusion Criteria:

• Volunteering to participate

• Having performed a liver transplant over the age of 50

• Spontaneous breathing

• Being hemodynamically stable

• Ability to read and write

• Not having an orthopedic disability and functional capacity limitation

• Being conscious and cooperative

Exclusion Criteria:

• Not agreeing to participate in the study

• Not continuing the treatment regularly

• Having neurological or neuropsychiatric problems

• Being colorblind

Related Conditions & MeSH terms

• Liver Transplantation

Intervention

Other:
• exercise
Application of two different exercises to liver transplant individuals.

Locations

Country	Name	City	State
Turkey	Hasan Kalyoncu University	Gaziantep

Sponsors (1)

Lead Sponsor	Collaborator
Hasan Kalyoncu University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Evaluation of Cognitive Functions	The Montreal Cognitive Assessment Scale will be used to evaluate cognitive functions. The score is between 0-30 points. In order to be considered as a cognitive disorder, the participant must get a score below 21 points.	One day
Primary	Evaluation of Cognitive Functions	The Montreal Cognitive Assessment Scale will be used to evaluate cognitive functions. The score is between 0-30 points. In order to be considered as a cognitive disorder, the participant must get a score below 21 points. A day before the rehabilitation	One day before the rehabilitation
Primary	Evaluation of Balance	Functional reach and timed get-go test were used for dynamic balance assessment, and single-leg standing tests were used for static balance assessment. A day before the rehabilitation	One day before the rehabilitation
Primary	Evaluation of Balance	Functional reach and timed get-go test were used for dynamic balance assessment, and single-leg standing tests were used for static balance assessment.At the time of discharge	One day
Primary	Assessment of functional capacity	In order to determine the functional capacity, a 6-minute walking test was applied. A day before the rehabilitation	One day before the rehabilitation
Primary	Assessment of functional capacity	In order to determine the functional capacity, a 6-minute walking test was applied.At the time of discharge	One day