Implementation of an Enhanced Rehabilitation Protocol After Liver Transplantation: Feasibility and Analysis of Results

Liver Transplant Disorder Clinical Trial

— IPRA  

Official title:

Implementation of an Enhanced Rehabilitation Protocol After Liver Transplantation: Feasibility and Analysis of Results

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05625139
• Other study ID #: 7906
• Status: Completed
• Start date: September 14, 2020
• Est. completion date: November 14, 2021

Study information

• Verified date: November 2022
• Source: University Hospital, Strasbourg, France
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Currently, there are no expert recommendations regarding enhanced rehabilitation after liver transplantation. The development of Enhanced Rehabilitation After Surgery (ERAS) protocols in major surgery, particularly cardiothoracic surgery, has motivated some anesthesia teams to extubate liver transplant patients earlier who meet predefined criteria (young patient, absence of comorbidities, absence of intraoperative transfusion) in order to limit the occurrence of complications of mechanical ventilation (pneumopathies, tracheal wound, muscle loss, etc.) On the other hand, improved rehabilitation in this case was often synonymous with early extubation in the operating room. Few studies, on the other hand, relate the implementation of a complete rehabilitation protocol including pre-, intra- and postoperative guidelines.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: November 14, 2021
• Est. primary completion date: September 14, 2021
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion criteria:

• Major subject operated at HUS for a liver transplant whose management was scheduled in the Surgical Intensive Care Unit fbetween December 01, 2018 and August 31, 2020

• Subject who does not question, after information, the reuse of his data for the purpose of this research

Exclusion criteria:

• Subject having expressed his opposition to participate in the study

• Liver transplant patient hospitalized in the Medical Intensive Care Unit before or after the surgery

Related Conditions & MeSH terms

• Liver Transplant Disorder

Locations

Country	Name	City	State
France	Service d'Anesthésie, Réanimation et Médecine péri-Opératoire - CHU de Strasbourg - France	Strasbourg

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Retrospective description of the protocol of improved rehabilitation after liver transplantation, to study the possibility of its implementation in the anesthesia-intensive care department and to analyze the first results		Files analysed retrospectively from December 01, 2018 to August 31, 2020 will be examined